Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 7/20 | 0.48 |
| ▸ | HTR2B | P41595 | 6/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14038424 | 0.81 | HDAC4 (0.56) | ALDH1A1HDAC4SLC9A1HPGDDEGS1 | |
| SCHEMBL13911289 | 0.81 | HDAC4 (0.56) | ALDH1A1HDAC4SLC9A1HPGDDEGS1 | |
| SCHEMBL6560499 | 0.81 | HDAC4 (0.56) | ALDH1A1HDAC4SLC9A1HPGDDEGS1 | |
| SCHEMBL26290355 | 0.81 | HDAC4 (0.56) | ALDH1A1HDAC4SLC9A1HPGDDEGS1 | |
| SCHEMBL14038418 | 0.81 | HDAC4 (0.56) | ALDH1A1HDAC4SLC9A1HPGDDEGS1 | |
| SCHEMBL5816055 | 0.79 | SLC9A1 (0.66) | ALDH1A1HDAC4SLC9A1HPGDHTR2C | |
| SCHEMBL12836827 | 0.79 | SLC9A1 (0.66) | ALDH1A1HDAC4SLC9A1HPGDHTR2C | |
| SCHEMBL4130704 | 0.79 | SLC9A1 (0.66) | ALDH1A1HDAC4SLC9A1HPGDHTR2C | |
| SCHEMBL871538 | 0.79 | SLC9A1 (0.66) | ALDH1A1HDAC4SLC9A1HPGDHTR2C | |
| SCHEMBL1224903 | 0.79 | SLC9A1 (0.66) | ALDH1A1HDAC4SLC9A1HPGDHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2567959-A1 | 6-(4-Hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors | SANOFI (FR) | 2013-03-13 | — | — | EP | disclosed |