Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13911289 | 1.00 | HDAC4 (0.56) | HDAC4ALDH1A1HRH3SIGMAR1SLC9A1 | |
| SCHEMBL14038424 | 1.00 | HDAC4 (0.56) | HDAC4ALDH1A1HRH3SIGMAR1SLC9A1 | |
| SCHEMBL6560499 | 1.00 | HDAC4 (0.56) | HDAC4ALDH1A1HRH3SIGMAR1SLC9A1 | |
| SCHEMBL14038418 | 1.00 | HDAC4 (0.56) | HDAC4ALDH1A1HRH3SIGMAR1SLC9A1 | |
| SCHEMBL17029589 | 0.83 | HRH3 (0.51) | HDAC4ALDH1A1HRH3SIGMAR1SLC9A1 | |
| SCHEMBL28004384 | 0.82 | SLC9A1 (0.54) | ALDH1A1HRH3SLC9A1HPGDGPR88 | |
| SCHEMBL14767822 | 0.81 | ALDH1A1 (0.59) | HDAC4ALDH1A1SIGMAR1SLC9A1HPGD | |
| SCHEMBL6560503 | 0.81 | HDAC4 (0.51) | HDAC4ALDH1A1HRH3SIGMAR1SLC9A1 | |
| SCHEMBL6560500 | 0.81 | HDAC4 (0.51) | HDAC4ALDH1A1HRH3SIGMAR1SLC9A1 | |
| SCHEMBL21093386 | 0.80 | NAMPT (0.55) | GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11732005-B2 | Peptidomimetic proteasome inhibitors | CORNELL UNIVERSITY (US) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11732005-B2 | Peptidomimetic proteasome inhibitors | PSMB1, PSMB3, PSMB11 | HDAC4 563/4885ALDH1A1 4635/4885HRH3 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.