Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 6/20 | 0.52 |
| ▸ | GSK3A | P49840 | 3/20 | 0.49 |
| ▸ | GSK3B | P49841 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14768735 | 0.81 | PIM1 (0.62) | PIM1ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL9996823 | 0.78 | PIM1 (0.51) | PIM1GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL9996735 | 0.75 | PIM1 (0.43) | PIM1GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL9996827 | 0.73 | PDE10A (0.47) | PIM1GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL31227216 | 0.72 | PPARA (0.40) | PIM1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL19848719 | 0.72 | KDM4E (0.53) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL4868335 | 0.72 | SLC9A1 (0.41) | KDM4ELMNA | |
| SCHEMBL11851657 | 0.71 | KDM4E (0.50) | PIM1GSK3AGSK3BALDH1A1KDM4E | |
| SCHEMBL24024712 | 0.70 | ALDH1A1 (0.52) | PIM1GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL540987 | 0.70 | MAPK1 (0.56) | MEN1KMT2AALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065883-A1 | Triazolo [4, 5- B] Pyridin Derivatives | Centro Nacional de Investigaceiones Oncologicas (CNIO) (ES) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065883-A1 | Triazolo [4, 5- B] Pyridin Derivatives | PIM1, PIM3, PIM2 | PIM1 1/4885GSK3A 389/4885GSK3B 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.