SCHEMBL14768837

SCHEMBL14768837

CCCCCCCCCCCCCCCCCCCCc1ccc(-c2nc3c(Br)ccc(Br)c3nc2-c2ccc(CCCCCCCCCCCCCCCCCCCC)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.48
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 3/20 0.48
MEN1 O00255 2/20 0.48
MAPT P10636 2/20 0.48
KMT2A Q03164 2/20 0.48
RAB9A P51151 2/20 0.48
USP2 O75604 1/20 0.48
GAA P10253 1/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 1/20 0.47
ESR1 P03372 2/20 0.47
ADRA2A P08913 2/20 0.47
ADORA3 P0DMS8 2/20 0.47
TACR2 P21452 2/20 0.47
SLC6A2 P23975 2/20 0.47
SLC6A4 P31645 2/20 0.47
SLC6A3 Q01959 2/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14789198 0.94 RAB9A (0.46) HSD17B10ALDH1A1KDM4EMEN1MAPT
SCHEMBL14819235 0.94 HSD11B1 (0.54) HSD17B10ALDH1A1KDM4EMEN1MAPT
SCHEMBL14763082 0.89 MEN1 (0.50) HSD17B10ALDH1A1KDM4EMEN1MAPT
SCHEMBL6736726 0.88 HSD17B10 (0.55) HSD17B10ALDH1A1KDM4EMEN1MAPT
SCHEMBL14789199 0.88 HSD11B1 (0.43) ALDH1A1MAPTRAB9AGAASMN1; SMN2
SCHEMBL14762724 0.84 CYP3A4 (0.45) HSD17B10ALDH1A1KDM4EMEN1MAPT
SCHEMBL24422612 0.83 KDM4E (0.51) HSD17B10ALDH1A1KDM4EMEN1MAPT
SCHEMBL24422614 0.81 KDM4E (0.43) HSD17B10ALDH1A1KDM4EMEN1MAPT
SCHEMBL14182502 0.80 NR5A1 (0.49) HSD17B10ALDH1A1KDM4EMAPTRAB9A
SCHEMBL14182510 0.80 NR5A1 (0.49) HSD17B10ALDH1A1KDM4EMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8853348-B2 Conjugated polymer containing dithienopyrrole-quinoxaline, preparation method and uses thereof OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2014-10-07 US disclosed
US-8853348-B2 Conjugated polymer containing dithienopyrrole-quinoxaline, preparation method and uses thereof OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2014-10-07 US disclosed
US-20130066043-A1 Conjugated Polymer Containing Dithienopyrrole-Quinoxaline, Preparation Method and Uses Thereof OCEAN'S KING LIGHT SCIENCE & TECHNOLOGY CO., LTD. 2013-03-14 US disclosed