SCHEMBL14768899

CCC(C)(C)[C@@H](OC(C)=O)C(C[C@@H](C)[C@H]1CC(=O)[C@@]2(C)C3CC[C@H]4C(C)(C)[C@@H](O[C@@H](C=O)OCC=O)CC[C@@]45C[C@@]35CC[C@]12C)OC

nearest known ligand 0.33

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	PSEN1	P49768	19/20	0.33

▸	PSEN2	P49810	19/20	0.33

▸	APH1B	Q8WW43	19/20	0.33

▸	NCSTN	Q92542	19/20	0.33

▸	APH1A	Q96BI3	19/20	0.33

▸	PSENEN	Q9NZ42	19/20	0.33

▸	PTPN11	Q06124	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14753721	0.94	PSEN1 (0.36)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14773587	0.81	PSEN1 (0.40)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14768574	0.79	ACLY (0.33)	—
SCHEMBL14773157	0.79	ACLY (0.33)	—
SCHEMBL14755824	0.75	PSEN1 (0.56)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL12331565	0.72	APP (0.49)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14755395	0.70	APP (0.41)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14755345	0.69	APP (0.53)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14753715	0.68	PSEN1 (0.67)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14755870	0.68	PSEN1 (0.67)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013036679-A1	COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS	SATORI PHARMACEUTICALS, INC. (US)	2013-03-14	—	—	WO	disclosed