SCHEMBL14769061

SCHEMBL14769061

CCCCN1COc2ccc(C(C)(C)c3ccc4c(c3)CN(CCC[Si](OCC)(OCC)OCC)CO4)cc2C1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16864098 0.97 CYP3A4 (0.31) MEN1KMT2AATMRXFP1
SCHEMBL23623361 0.94 ALDH1A1 (0.30)
SCHEMBL23622817 0.88
SCHEMBL14726006 0.88 HRH3 (0.32)
SCHEMBL14726005 0.83 CYP3A4 (0.30)
SCHEMBL21160851 0.82 CYP2D6 (0.33)
SCHEMBL13888247 0.81 S1PR1 (0.40) MEN1KMT2AATMRXFP1
SCHEMBL112090 0.80 MEN1 (0.36) MEN1KMT2AATMRXFP1
SCHEMBL2596964 0.79 CYP2D6 (0.38) MEN1KMT2AATMRXFP1
SCHEMBL13888249 0.78 CYP3A4 (0.38) MEN1KMT2AATMRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140316045-A1 Silicone Resins DOW CORNING CORPORATION (US) 2014-10-23 US disclosed
US-20130065992-A1 Polymer Compositions Containing Oxazine-Based Alkoxysilanes DOW CORNING CORPORATION (US) 2013-03-14 US disclosed