SCHEMBL2596964

SCHEMBL2596964

CCO[Si](CCCN1COc2ccccc2C1)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
ALDH1A1 P00352 2/20 0.38
APP P05067 1/20 0.36
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 1/20 0.32
HIF1A Q16665 1/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
ATM Q13315 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
HTR1A P08908 3/20 0.31
DRD2 P14416 3/20 0.31
HTR7 P34969 3/20 0.31
HTR2B P41595 3/20 0.31
HTR2A P28223 2/20 0.31
DRD3 P35462 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2596952 0.90 CYP2D6 (0.38) CYP2D6CYP1A2CYP2C19ALDH1A1APP
SCHEMBL13888246 0.83 KMT2A (0.41) ALDH1A1KMT2AMEN1ATMRXFP1
SCHEMBL16864098 0.81 CYP3A4 (0.31) CYP2D6CYP3A4HIF1AKMT2AMEN1
SCHEMBL14463277 0.81 ALDH1A1 (0.54) CYP2D6CYP1A2CYP2C19ALDH1A1APP
SCHEMBL13169006 0.81 APP (0.37) CYP2D6CYP1A2CYP2C19ALDH1A1APP
SCHEMBL13888249 0.79 CYP3A4 (0.38) CYP2D6ALDH1A1CYP3A4HIF1AKMT2A
SCHEMBL2577142 0.79 ALDH1A1 (0.61) CYP2D6CYP1A2CYP2C19ALDH1A1APP
SCHEMBL14768690 0.79 MAPT (0.53) ALDH1A1KMT2AMEN1ATMRXFP1
SCHEMBL13888247 0.79 S1PR1 (0.40) CYP2D6CYP1A2CYP2C19ALDH1A1CYP3A4
SCHEMBL14769061 0.79 MEN1 (0.31) KMT2AMEN1ATMRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117106184-A Preparation and reprocessing method of benzoxazine resin-based CANs based on Si-O-Ph bond double decomposition reaction 齐鲁工业大学(山东省科学院) 2023-11-24 CN disclosed
EP-2593497-B1 SILICONE RESINS AND THEIR USE IN POLYMER COMPOSITIONS DOW SILICONES CORP (US) 2018-06-20 EP disclosed
US-9006372-B2 Silicone resins and their use in polymer compositions DOW CORNING (SHANGHAI) CO LTD (CN) 2015-04-14 US disclosed
US-9006372-B2 Silicone resins and their use in polymer compositions DOW CORNING (SHANGHAI) CO LTD (CN) 2015-04-14 US disclosed
US-20140316045-A1 Silicone Resins DOW CORNING CORPORATION (US) 2014-10-23 US disclosed
US-20140303299-A1 Silicone Resins And Their Use in Polymers DOW CORNING CORPORATION 2014-10-09 US disclosed
US-20140303299-A1 Silicone Resins And Their Use in Polymers DOW CORNING CORPORATION 2014-10-09 US disclosed
EP-2780399-A2 SILICONE RESINS COMPRISING METALLOSILOXANE Dow Corning Corporation (US) 2014-09-24 EP disclosed
EP-2780398-A1 SILICONE RESINS AND THEIR USE IN POLYMERS Dow Corning Corporation (US) 2014-09-24 EP disclosed
US-20140249257-A1 Silicone Resins Comprising Metallosiloxane DOW CORNING CORPORATION (US) 2014-09-04 US disclosed
EP-2571937-A2 POLYMER COMPOSITIONS CONTAINING OXAZINE-BASED ALKOXYSILANES Dow Corning Corporation (US) 2013-03-27 EP disclosed
US-20130065993-A1 Polymer Compositions Containing Alkoxysilanes DOW CORNING CORPORATION (US) 2013-03-14 US disclosed
US-20130065993-A1 Polymer Compositions Containing Alkoxysilanes DOW CORNING CORPORATION (US) 2013-03-14 US disclosed
US-20130065992-A1 Polymer Compositions Containing Oxazine-Based Alkoxysilanes DOW CORNING CORPORATION (US) 2013-03-14 US disclosed
US-20130065992-A1 Polymer Compositions Containing Oxazine-Based Alkoxysilanes DOW CORNING CORPORATION (US) 2013-03-14 US disclosed
US-20130066009-A1 Silicone Resins And Their Use In Polymer Compositions DOW CORNING CORPORATION (US) 2013-03-14 US disclosed
US-20130066009-A1 Silicone Resins And Their Use In Polymer Compositions DOW CORNING CORPORATION (US) 2013-03-14 US disclosed
WO-2011143931-A1 SILICONE RESINS AND THEIR USE IN POLYMER COMPOSITIONS DOW CORNING CORPORATION (US) 2011-11-24 WO disclosed
WO-2011143930-A1 POLYMER COMPOSITIONS CONTAINING ALKOXYSILANES DOW CORNING CORPORATIOM (US) 2011-11-24 WO disclosed
WO-2011144575-A2 POLYMER COMPOSITIONS CONTAINING OXAZINE-BASED ALKOXYSILANES DOW CORNING CORPORATION (US) 2011-11-24 WO disclosed