SCHEMBL1476933

SCHEMBL1476933

COc1c(N)ccc2cc(C(=O)O)ccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.54
PTPN1 P18031 1/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA12 O43570 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA7 P43166 1/20 0.45
TPMT P51580 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
HTT P42858 2/20 0.42
CDC25B P30305 1/20 0.42
RARA P10276 2/20 0.42
RARB P10826 2/20 0.42
RARG P13631 2/20 0.42
LMNA P02545 2/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7572866 0.83 TPMT (0.59) KDM4EPTPN1CA1CA2CA12
SCHEMBL1434455 0.83 ESR1 (0.56) KDM4EPTPN1CA1CA2CA12
SCHEMBL1476496 0.79 PTPN1 (0.49) KDM4EPTPN1HTTCDC25BRARA
SCHEMBL6007565 0.78 PTPN1 (0.51) KDM4EPTPN1CA1CA2CA12
SCHEMBL27976709 0.78 KDM4E (0.54) KDM4EPTPN1CA1CA2CA12
SCHEMBL10835777 0.78 TSHR (0.61) KDM4EPTPN1CA1CA2CA12
SCHEMBL28017898 0.77 TPMT (0.56) KDM4EPTPN1CA1CA2CA12
SCHEMBL342574 0.77 PTPN1 (0.50) KDM4EPTPN1CA1CA2CA12
SCHEMBL28205088 0.77 PTPN1 (0.50) KDM4EPTPN1CA1CA2CA12
SCHEMBL29223974 0.77 ESR1 (0.50) KDM4EPTPN1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8496616-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-30 US disclosed
EP-1991286-B1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENT LTD (BB) 2012-12-26 EP disclosed
US-20120220932-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-08-30 US disclosed
US-8187492-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-05-29 US disclosed
US-20110092999-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-04-21 US disclosed
US-7914485-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-29 US disclosed
US-7857785-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-12-28 US disclosed
US-20100145269-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-06-10 US disclosed
US-7662129-B2 Block copolymer containing A block is a liquid crystal polymer block formed from repeating units comprising mesogenic groups and has a polymer backbone comprising no aliphatic unsaturation; and the B block is a non-liquid crystal polymer block; catheters BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-02-16 US disclosed
US-20100016941-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-01-21 US disclosed
US-20070191813-A1 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. 2007-08-16 US disclosed
US-6143823-A POLYESTER, POLYAMIDE, POLYETHER, POLYCARBONATE, POLYLACTAM, AND/OR POLYLACTONE CONDENSATES BLENDED WITH OLEFIN POLYMER; IMPACT AND TENSILE STRENGTH; CHEMICAL AND HEAT RESISTANCE BAYER AG (DE) 2000-11-07 US disclosed
EP-0432561-B1 Graft cocondensate made of a polyarylenesulfide backbone and side chains with liquid crystal properties BAYER AG (DE) 1995-06-07 EP disclosed
EP-0330037-B1 Thermoplastic block copolymers comprising blocks of carboxyl groups containing polypropylene and blocks of completely aromatic polyesters, polyestercarbonates or polyesteramides. BAYER AG (DE) 1993-04-21 EP disclosed
US-5162434-A Molded articles, filaments, fibers, films BAYER AKTIENGESELLSCHAFT (DE) 1992-11-10 US disclosed
US-5030703-A Polyesters, polycarbonateesters, polylactones BAYER AKTIENGESELLSCHAFT (DE) 1991-07-09 US disclosed
EP-0432561-A2 Graft cocondensate made of a polyarylenesulfide backbone and side chains with liquid crystal properties BAYER AG (DE) 1991-06-19 EP disclosed
US-4975522-A Crosslinkable compounds and method for making Adademie der Wissenschaften der DDR (DD) 1990-12-04 US disclosed
EP-0359038-A2 Liquid crystalline polycondensates with a high thermal stability, process for making them and their use in producing moulded articles, films, fibres and filaments BAYER AG (DE) 1990-03-21 EP disclosed
EP-0330037-A1 Thermoplastic block copolymers comprising blocks of carboxyl groups containing polypropylene and blocks of completely aromatic polyesters, polyestercarbonates or polyesteramides. BAYER AG (DE) 1989-08-30 EP disclosed