Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | RECQL | P46063 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16736818 | 0.83 | TRPA1 (0.69) | TRPA1PTGS1CACNA1CKDM4ETDP1 | |
| SCHEMBL17424101 | 0.83 | TRPA1 (0.69) | TRPA1PTGS1CACNA1CKDM4ETDP1 | |
| SCHEMBL4371198 | 0.83 | TRPA1 (0.69) | TRPA1PTGS1CACNA1CKDM4ETDP1 | |
| SCHEMBL921036 | 0.79 | TRPA1 (0.75) | TRPA1PTGS1CACNA1CKDM4ETDP1 | |
| Carvacrol SCHEMBL29544247 | 0.79 | PTGS1 (1.00) | TRPA1PTGS1CACNA1CKDM4ETDP1 | |
| Carvacrol SCHEMBL5326397 | 0.79 | PTGS1 (1.00) | TRPA1PTGS1CACNA1CKDM4ETDP1 | |
| Carvacrol SCHEMBL24734 | 0.79 | PTGS1 (1.00) | TRPA1PTGS1CACNA1CKDM4ETDP1 | |
| Carvacrol SCHEMBL1668461 | 0.77 | PTGS1 (0.95) | TRPA1PTGS1CACNA1CKDM4ETDP1 | |
| Carvacrol SCHEMBL5031273 | 0.77 | PTGS1 (0.95) | TRPA1PTGS1CACNA1CKDM4ETDP1 | |
| Carvacrol SCHEMBL7075922 | 0.77 | PTGS1 (0.95) | TRPA1PTGS1CACNA1CKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9428524-B2 | Synthetic process for the manufacture of ecteinascidin compounds | PHARMA MAR, S.A. (ES) | 2016-08-30 | — | — | US | disclosed |
| US-20130066067-A1 | Synthetic Process for the Manufacture of Ecteinascidin Compounds | PHARMA MAR, S.A. (ES) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130066067-A1 | Synthetic Process for the Manufacture of Ecteinascidin Compounds | SERPINH1, ERLIN2, PTMA | TRPA1 4293/4885PTGS1 911/4885CACNA1C 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.