SCHEMBL921036

SCHEMBL921036

Cc1ccc(C(C)c2ccc(C)c(O)c2)cc1O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.75
PTGS1 P23219 1/20 0.75
CACNA1C Q13936 1/20 0.75
TSHR P16473 2/20 0.48
CASP1 P29466 1/20 0.48
ESR1 P03372 1/20 0.48
PDCD1 Q15116 1/20 0.48
ESR2 Q92731 1/20 0.48
CD274 Q9NZQ7 1/20 0.48
ACHE P22303 1/20 0.45
KDM4E B2RXH2 5/20 0.42
MAPT P10636 4/20 0.42
HIF1A Q16665 3/20 0.42
ALOX15 P16050 2/20 0.42
HSD17B10 Q99714 2/20 0.42
ALDH1A1 P00352 2/20 0.42
ALOX12 P18054 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921222 0.92 TRPA1 (0.64) TRPA1PTGS1CACNA1CTSHRCASP1
Carvacrol SCHEMBL29544247 0.86 PTGS1 (1.00) TRPA1PTGS1CACNA1CTSHRCASP1
Carvacrol SCHEMBL5326397 0.86 PTGS1 (1.00) TRPA1PTGS1CACNA1CTSHRCASP1
Carvacrol SCHEMBL24734 0.86 PTGS1 (1.00) TRPA1PTGS1CACNA1CTSHRCASP1
Carvacrol SCHEMBL7075922 0.84 PTGS1 (0.95) TRPA1PTGS1CACNA1CTSHRCASP1
Carvacrol SCHEMBL1668461 0.84 PTGS1 (0.95) TRPA1PTGS1CACNA1CTSHRCASP1
Carvacrol SCHEMBL29152253 0.84 PTGS1 (0.95) TRPA1PTGS1CACNA1CTSHRCASP1
Carvacrol SCHEMBL5030301 0.84 PTGS1 (0.95) TRPA1PTGS1CACNA1CTSHRCASP1
Carvacrol SCHEMBL5031273 0.84 PTGS1 (0.95) TRPA1PTGS1CACNA1CTSHRCASP1
Carvacrol SCHEMBL31732819 0.84 PTGS1 (0.95) TRPA1PTGS1CACNA1CTSHRCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 US disclosed
EP-1770447-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY MITSUBISHI CHEM CORP (JP) 2011-03-16 EP disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
US-20100183332-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-07-22 US disclosed
EP-2154575-A2 Electrophotographic photoreceptor Mitsubishi Chemical Corporation (JP) 2010-02-17 EP disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed
EP-1770447-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Mitsubishi Chemical Corporation (JP) 2007-04-04 EP disclosed