Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14752623 | 0.80 | S1PR2 (0.47) | S1PR2MEN1KMT2AS1PR5MAPT | |
| SCHEMBL14769544 | 0.79 | S1PR2 (0.36) | S1PR2PPARAPPARGMEN1KMT2A | |
| SCHEMBL14769540 | 0.68 | S1PR2 (0.36) | S1PR2MEN1KMT2AS1PR5MAPT | |
| SCHEMBL10254524 | 0.66 | TSHR (0.41) | PPARAPPARGMEN1KMT2AMAPT | |
| SCHEMBL1694840 | 0.66 | NR3C1 (0.41) | PPARAPPARGMEN1KMT2AMAPT | |
| SCHEMBL3717109 | 0.65 | TDP1 (0.48) | PPARAPPARGMAPTKDM4EALDH1A1 | |
| SCHEMBL14769545 | 0.65 | S1PR2 (0.34) | S1PR2MEN1KMT2AS1PR5MAPT | |
| SCHEMBL14919744 | 0.64 | CFTR (0.46) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL14752625 | 0.64 | ALDH1A1 (0.46) | S1PR2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL31347270 | 0.64 | KDM4E (0.40) | PPARAPPARGMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846712-B2 | 6-(4-hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors | SANOFI (FR) | 2014-09-30 | — | — | US | disclosed |
| US-20130065894-A1 | 6-(4-HYDROXY-PHENYL)-3-STYRYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS | SANOFI (FR) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065894-A1 | 6-(4-HYDROXY-PHENYL)-3-STYRYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS | MAP3K1, MAP4K2, MAP3K6 | S1PR2 761/4885PPARA 1289/4885PPARG 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.