SCHEMBL14769556

SCHEMBL14769556

CC1(C)c2ccccc2-c2cc3c4ccccc4n(-c4ccc(-c5nc6ccccc6n5-c5cccc(-c6cc(-c7cc(-c8ccccc8)cc(-c8ccccc8)c7)cc(-c7cc(-c8ccccc8)cc(-c8ccccc8)c7)c6)c5)cc4)c3cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
PTGER4 P35408 1/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
GRIA1 P42261 1/20 0.37
CACNG8 Q8WXS5 1/20 0.37
CACNG2 Q9Y698 1/20 0.37
GAA P10253 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 8/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MAPT P10636 1/20 0.35
RECQL P46063 1/20 0.35
PTGS2 P35354 1/20 0.34
HTT P42858 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15930445 0.93 ESR1 (0.41) ESR1ESR2PTGER4HDAC1HDAC8
SCHEMBL802020 0.93 ESR1 (0.45) ESR1ESR2PTGER4HDAC1HDAC8
SCHEMBL15930446 0.92 ESR1 (0.41) ESR1ESR2PTGER4HDAC1HDAC8
SCHEMBL15930324 0.92 ESR1 (0.48) ESR1ESR2PTGER4HDAC1HDAC8
SCHEMBL12836942 0.90 ESR1 (0.34) ESR1ESR2PTGER4HDAC1HDAC8
SCHEMBL12114842 0.90 ESR1 (0.40) ESR1ESR2PTGER4HDAC1HDAC8
SCHEMBL14849844 0.90 ESR1 (0.47) ESR1ESR2PTGER4HDAC1HDAC8
SCHEMBL12455954 0.89 PDE10A (0.36) ESR1ESR2PTGER4GAAMEN1
SCHEMBL15930410 0.89 ESR1 (0.41) ESR1ESR2PTGER4HDAC1HDAC8
SCHEMBL2603508 0.89 ESR1 (0.45) ESR1ESR2PTGER4HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10833281-B2 Organic electroluminescence composition, material for organic electroluminescence element, solution of material for organic electroluminescence element, and organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-11-10 US disclosed
US-10714691-B2 Formulations for the production of electronic devices MERCK PATENT GMBH (DE) 2020-07-14 US disclosed
US-20190207114-A9 FORMULATIONS AND ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-07-04 US disclosed
EP-2477999-B1 FORMULATIONS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-01-23 EP disclosed
US-20180114912-A1 FORMULATIONS AND ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-04-26 US disclosed
US-20180114912-A1 FORMULATIONS AND ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-04-26 US disclosed
US-9882135-B2 Formulations and electronic devices MERCK PATENT GMBH (DE) 2018-01-30 US disclosed
US-9882135-B2 Formulations and electronic devices MERCK PATENT GMBH (DE) 2018-01-30 US disclosed
US-20170125676-A1 FORMULATIONS FOR THE PRODUCTION OF ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-05-04 US disclosed
US-20170125676-A1 FORMULATIONS FOR THE PRODUCTION OF ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-05-04 US disclosed
US-9159930-B2 Formulations and electronic devices MERCK PATENT GMBH (DE) 2015-10-13 US disclosed
US-9159930-B2 Formulations and electronic devices MERCK PATENT GMBH (DE) 2015-10-13 US disclosed
EP-2517277-B1 COMPOSITION FOR THE PREPARATION OF ORGANIC ELECTRONIC (OE) DEVICES MERCK PATENT GMBH (DE) 2015-07-08 EP disclosed
US-8974702-B2 Composition for the preparation of organic electronic (OE) devices MERCK PATENT GMBH (DE) 2015-03-10 US disclosed
US-8974702-B2 Composition for the preparation of organic electronic (OE) devices MERCK PATENT GMBH (DE) 2015-03-10 US disclosed
WO-2015018480-A1 FORMULATION FOR THE PREPARATION OF ORGANIC ELECTRONIC (OE) DEVICES COMPRISING A POLYMERIC BINDER MERCK PATENT GMBH (DE) 2015-02-12 WO disclosed
US-20140048745-A1 FORMULATIONS AND ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2014-02-20 US disclosed
US-20140048745-A1 FORMULATIONS AND ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2014-02-20 US disclosed
US-20130062581-A1 COMPOSITION FOR THE PREPARATION OF ORGANIC ELECTRONIC (OE) DEVICES MERCK PATENT GMBH (DE) 2013-03-14 US disclosed
US-20130062581-A1 COMPOSITION FOR THE PREPARATION OF ORGANIC ELECTRONIC (OE) DEVICES MERCK PATENT GMBH (DE) 2013-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10833281-B2 Organic electroluminescence composition, material for organic electroluminescence element, solution of material for organic electroluminescence element, and organic electroluminescence element SLCO4C1, SLCO2A1, SLCO1A2 ESR1 102/4885ESR2 280/4885PTGER4 2102/4885
US-20180114912-A1 FORMULATIONS AND ELECTRONIC DEVICES SLC19A1, IK, KCNQ2 ESR1 170/4885ESR2 510/4885PTGER4 540/4885
US-20170125676-A1 FORMULATIONS FOR THE PRODUCTION OF ELECTRONIC DEVICES NR3C2, KCNE1, NR2E1 ESR1 677/4885ESR2 81/4885PTGER4 794/4885
US-20190207114-A9 FORMULATIONS AND ELECTRONIC DEVICES SLC19A1, IK, KCNQ2 ESR1 170/4885ESR2 510/4885PTGER4 540/4885
US-10714691-B2 Formulations for the production of electronic devices NR3C2, KCNE1, NR2E1 ESR1 628/4885ESR2 85/4885PTGER4 786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.