Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12470770 | 0.82 | ALOX5 (0.57) | ALOX5NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL14769659 | 0.82 | PDGFRB (0.57) | ALOX5NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL9127192 | 0.81 | ALOX5 (0.73) | ALOX5NPC1RAB9ACYP3A4MEN1 | |
| SCHEMBL25220382 | 0.79 | CYP4F2 (0.58) | ALOX5NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL31052328 | 0.79 | CYP4F2 (0.58) | ALOX5NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL23247030 | 0.79 | ALOX5 (0.53) | ALOX5NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL14784133 | 0.78 | PDGFRB (0.60) | ALOX5NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL4035810 | 0.77 | CYP3A4 (0.77) | ALOX5NPC1RAB9ACYP3A4MEN1 | |
| SCHEMBL27994380 | 0.77 | ALDH1A1 (0.57) | ALOX5NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL25258837 | 0.77 | PDGFRB (0.60) | ALOX5NPC1RAB9APDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065922-A1 | NOVEL AMIDES AS FUNGICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065922-A1 | NOVEL AMIDES AS FUNGICIDES | CYP51A1, DDT, CYP4X1 | ALOX5 2833/4885NPC1 2192/4885RAB9A 1375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.