SCHEMBL14769718

SCHEMBL14769718

CNC(=O)[C@@H](N)CCCNC(C)=N

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 6/20 0.49
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
RRM1 P23921 1/20 0.41
DPP8 Q6V1X1 4/20 0.38
DPP9 Q86TI2 4/20 0.38
DPP4 P27487 3/20 0.38
SLC15A1 P46059 1/20 0.38
OTC P00480 1/20 0.37
KISS1R Q969F8 1/20 0.34
NOD1 Q9Y239 1/20 0.34
NPY4R P50391 3/20 0.33
NPY1R P25929 2/20 0.33
NPY2R P49146 2/20 0.33
NPY5R Q15761 2/20 0.33
ANPEP P15144 1/20 0.33
RNPEP Q9H4A4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13319577 1.00 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL15165702 0.86 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL1388277 0.86 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL7326934 0.86 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL19368710 0.84 DPP7 (0.44) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL18542869 0.84 DPP7 (0.44) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL18542868 0.84 DPP7 (0.44) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL25446446 0.82 DPP7 (0.43) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL15165700 0.82 DPP7 (0.51) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL18594774 0.82 DPP7 (0.43) DPP7GNAI3GNAO1GNAI1RRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8759104-B2 Cationic lipids THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2014-06-24 US disclosed
US-20130065308-A1 CATIONIC LIPIDS THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2013-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130065308-A1 CATIONIC LIPIDS PLIN5, LPCAT3, IPO5 DPP7 2751/4885GNAI3 3099/4885GNAO1 2791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.