SCHEMBL7326934

SCHEMBL7326934

CNC(=O)[C@@H](N)CCCNC(=N)N

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.49
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
NPY4R P50391 11/20 0.42
NPY1R P25929 6/20 0.42
NPY2R P49146 4/20 0.42
NPY5R Q15761 4/20 0.42
RRM1 P23921 1/20 0.41
SLC15A1 P46059 1/20 0.38
OTC P00480 1/20 0.37
ALOX15 P16050 1/20 0.37
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15165702 1.00 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1NPY4R
SCHEMBL1388277 1.00 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1NPY4R
SCHEMBL17525174 0.95 DPP7 (0.51) DPP7GNAI3GNAO1GNAI1NPY4R
SCHEMBL13319577 0.86 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1NPY4R
SCHEMBL14769718 0.86 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1NPY4R
SCHEMBL15627730 0.86 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1NPY4R
SCHEMBL23610947 0.86 DPP7 (0.61) DPP7GNAI3GNAO1GNAI1NPY4R
SCHEMBL15165700 0.86 DPP7 (0.51) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL23626315 0.86 DPP7 (0.61) DPP7GNAI3GNAO1GNAI1NPY4R
SCHEMBL30483974 0.85 NPY4R (0.53) DPP7GNAI3GNAO1GNAI1NPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP disclosed
WO-2024249291-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF CASMA THERAPEUTICS, INC. (US) 2024-12-05 WO disclosed
WO-2024147125-A1 CYCLOBUTYL-SUBSTITUTED PHENOXY-DIOXETANES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-07-11 WO disclosed
EP-4219717-A2 EXON SKIPPING OLIGOMERS FOR MUSCULAR DYSTROPHY Sarepta Therapeutics, Inc. (US) 2023-08-02 EP disclosed
US-20220193246-A1 COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY SAREPTA THERAPEUTICS, INC. (US) 2022-06-23 US disclosed
US-10765760-B2 Exon skipping oligomer conjugates for muscular dystrophy SAREPTA THERAPEUTICS, INC. (US) 2020-09-08 US disclosed
US-10758629-B2 Exon skipping oligomer conjugates for muscular dystrophy SAREPTA THERAPEUTICS, INC. (US) 2020-09-01 US disclosed
WO-2020023688-A1 EXON SKIPPING OLIGOMERS FOR MUSCULAR DYSTROPHY SAREPTA THERAPEUTICS, INC. (US) 2020-01-30 WO disclosed
US-20180200286-A1 METHODS AND COMPOSITIONS FOR TREATING WOUNDS UTILIZING CHITOSAN COMPOUNDS UNITED STATES GOVERNMENT 2018-07-19 US disclosed
EP-2391636-B1 ANTIBIOTIC PEPTIDES AMP-THERAPEUTICS GMBH (DE) 2017-09-27 EP disclosed
US-20170119810-A1 METHODS AND COMPOSITIONS FOR TREATING WOUNDS UTILIZING CHITOSAN COMPOUNDS UNITED STATES GOVERNMENT 2017-05-04 US disclosed
WO-2012122422-A2 ACTIVE AGENT PRODRUGS WITH HETEROCYCLIC LINKERS SIGNATURE THERAPEUTICS, INC. (US) 2012-09-13 WO disclosed
EP-0680469-B1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME BOEHRINGER INGELHEIM PHARMA (DE) 2000-04-26 EP disclosed
WO-1992007568-A1 η-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1992-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220193246-A1 COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY UTRN, EDNRA, MTPN DPP7 2283/4885GNAI3 1241/4885GNAO1 1905/4885
US-10765760-B2 Exon skipping oligomer conjugates for muscular dystrophy SMN1; SMN2, UTRN, RBM17 DPP7 1299/4885GNAI3 3246/4885GNAO1 2566/4885
US-20180200286-A1 METHODS AND COMPOSITIONS FOR TREATING WOUNDS UTILIZING CHITOSAN COMPOUNDS CHIA, MMP8, CHIT1 DPP7 550/4885GNAI3 3143/4885GNAO1 3506/4885
US-10758629-B2 Exon skipping oligomer conjugates for muscular dystrophy UTRN, SMN1; SMN2, RBM17 DPP7 1325/4885GNAI3 3169/4885GNAO1 2522/4885
US-20170119810-A1 METHODS AND COMPOSITIONS FOR TREATING WOUNDS UTILIZING CHITOSAN COMPOUNDS CHIA, MMP8, CHIT1 DPP7 550/4885GNAI3 3143/4885GNAO1 3506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.