SCHEMBL14769838

SCHEMBL14769838

CN1/C(=C/c2c(O)c(=O)c2=O)C(C)(C)c2cc(OC=O)ccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 14/20 0.39
KDM4E B2RXH2 11/20 0.39
HTT P42858 8/20 0.39
MEN1 O00255 8/20 0.39
KMT2A Q03164 8/20 0.39
LMNA P02545 5/20 0.35
ALDH1A1 P00352 6/20 0.33
POLB P06746 4/20 0.33
GAA P10253 3/20 0.33
RECQL P46063 2/20 0.33
MAPK1 P28482 6/20 0.33
GPR55 Q9Y2T6 2/20 0.33
TSHR P16473 2/20 0.32
HSD17B10 Q99714 2/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
USP2 O75604 3/20 0.32
NPSR1 Q6W5P4 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14769835 0.86 MEN1 (0.34) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL10111632 0.84 PTPN1 (0.37)
SCHEMBL10015884 0.83 MAPT (0.39) MAPTKDM4EHTTMEN1KMT2A
SCHEMBL4807513 0.81 LMNA (0.43) MAPTKDM4EHTTMEN1KMT2A
SCHEMBL4807510 0.81 LMNA (0.43) MAPTKDM4EHTTMEN1KMT2A
SCHEMBL3853022 0.78 LMNA (0.55) MAPTKDM4EHTTMEN1KMT2A
SCHEMBL3853014 0.78 LMNA (0.55) MAPTKDM4EHTTMEN1KMT2A
SCHEMBL12173798 0.77 MAPT (0.34) MAPTKDM4EHTTMEN1KMT2A
SCHEMBL19188641 0.74 HTT (0.39) MAPTKDM4EHTTMEN1KMT2A
SCHEMBL12173758 0.72 MAPT (0.35) MAPTKDM4EHTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130061929-A1 PHOTOELECTRIC CONVERSION ELEMENT, METHOD FOR PRODUCING PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-03-14 US disclosed