Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 11/20 | 0.55 |
| ▸ | HTT | P42858 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 11/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 10/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853022 | 1.00 | LMNA (0.55) | LMNAHTTMAPTKDM4EALDH1A1 | |
| SCHEMBL5522293 | 0.86 | MAPT (0.52) | LMNAHTTMAPTKDM4EALDH1A1 | |
| SCHEMBL14453270 | 0.86 | MAPT (0.52) | LMNAHTTMAPTKDM4EALDH1A1 | |
| SCHEMBL12156970 | 0.84 | MAPT (0.47) | LMNAHTTMAPTKDM4EALDH1A1 | |
| SCHEMBL14769839 | 0.84 | ALDH1A1 (0.47) | LMNAHTTMAPTKDM4EALDH1A1 | |
| SCHEMBL14093786 | 0.83 | LMNA (0.55) | LMNAHTTMAPTKDM4EALDH1A1 | |
| SCHEMBL15947424 | 0.83 | MAPT (0.47) | LMNAHTTMAPTKDM4EALDH1A1 | |
| SCHEMBL16319609 | 0.83 | MAPT (0.48) | LMNAHTTMAPTKDM4EALDH1A1 | |
| SCHEMBL14769832 | 0.83 | MAPT (0.48) | LMNAHTTMAPTKDM4EALDH1A1 | |
| SCHEMBL17627872 | 0.82 | LMNA (0.54) | LMNAHTTMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362884-B1 | A DYE COMPRISING A CHROMOPHORE TO WHICH AN ACYLOIN GROUP IS ATTACHED | SONY CORP (JP) | 2017-08-02 | — | — | EP | disclosed |
| US-9679702-B2 | Dye comprising a chromophore to which an acyloin group is attached | SONY CORPORATION (JP) | 2017-06-13 | — | — | US | disclosed |
| US-8378120-B2 | Method and reagent for measuring nitroreductase enzyme activity | GE HEALTHCARE UK LIMITED (GB) | 2013-02-19 | — | — | US | disclosed |
| US-20110265878-A1 | DYE COMPRISING A CHROMOPHORE TO WHICH AN ACYLOIN GROUP IS ATTACHED | SONY CORPORATION (JP) | 2011-11-03 | — | — | US | disclosed |
| US-20090325209-A1 | METHOD AND REAGENT FOR MEASURING NITROREDUCTASE ENZYME ACTIVITY | GE HEALTHCARE UK LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
| US-7579140-B2 | Method and reagent for measuring nitroreductase enzyme activity | GE HEALTHCARE UK LIMITED (GB) | 2009-08-25 | — | — | US | disclosed |
| US-20080317674-A1 | Method and Reagent for Measuring Nitroreductase Enzyme Activity | GE HEALTHCARE UK LIMITED (GB) | 2008-12-25 | — | — | US | disclosed |
| US-20070196767-A1 | Use Of Squaric Acid Dyes In Optical Layers For Optical Data Recording | CLARIANT INTERNATIONAL LTD (CH) | 2007-08-23 | — | — | US | disclosed |
| US-20070196767-A1 | Use Of Squaric Acid Dyes In Optical Layers For Optical Data Recording | CLARIANT INTERNATIONAL LTD (CH) | 2007-08-23 | — | — | US | disclosed |
| EP-1165693-A2 | SQUARAINE DYES | Amersham Pharmacia Biotech UK Limited (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058405-A2 | SQUARAINE DYES | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325209-A1 | METHOD AND REAGENT FOR MEASURING NITROREDUCTASE ENZYME ACTIVITY | CBR3, CBR1, ADH7 | LMNA 3842/4885HTT 4799/4885MAPT 4857/4885 |
| US-20080317674-A1 | Method and Reagent for Measuring Nitroreductase Enzyme Activity | CBR3, CBR1, SQOR | LMNA 3803/4885HTT 4796/4885MAPT 4851/4885 |
| US-20110265878-A1 | DYE COMPRISING A CHROMOPHORE TO WHICH AN ACYLOIN GROUP IS ATTACHED | ACOT7, ABHD5, MBOAT4 | LMNA 970/4885HTT 1647/4885MAPT 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.