SCHEMBL14770244

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14770243	0.88	KMT2A (0.56)	KCNH2CACNA1ICACNA1HCYP2D6HTR7
	SCHEMBL4272268	0.87	CACNA1I (0.65)	KCNH2CACNA1ICACNA1HCYP2D6POLB
	SCHEMBL14770219	0.86	CCR2 (0.56)	KCNH2CACNA1ICACNA1HCYP2D6POLB
	SCHEMBL14770218	0.85	CACNA1I (0.60)	KCNH2CACNA1ICACNA1HCYP2D6
	SCHEMBL4280587	0.85	CACNA1I (0.63)	KCNH2CACNA1ICACNA1HCYP2D6POLB
	SCHEMBL4272201	0.85	CACNA1I (0.77)	KCNH2CACNA1ICACNA1HCYP2D6POLB
	SCHEMBL8374124	0.85	KCNH2 (0.59)	KCNH2CACNA1ICACNA1HCYP2D6POLB
	SCHEMBL14770220	0.83	CHRM4 (0.56)	KCNH2CACNA1ICACNA1HCYP2D6HTR7
	SCHEMBL26081951	0.83	CACNA1I (0.59)	KCNH2CACNA1ICACNA1HCYP2D6
	SCHEMBL14770237	0.83	KCNH2 (0.53)	KCNH2CACNA1ICACNA1HCYP2D6CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.