Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.58 |
| ▸ | ANPEP | P15144 | 4/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15083833 | 0.80 | MMP2 (0.57) | MMP2ANPEPBRD4CYP1A2HIF1A | |
| SCHEMBL201253 | 0.80 | MMP2 (0.57) | MMP2ANPEPBRD4CYP1A2HIF1A | |
| SCHEMBL13403397 | 0.79 | MMP2 (0.60) | MMP2ANPEPBRD4CYP1A2HIF1A | |
| SCHEMBL2691165 | 0.79 | MMP2 (0.60) | MMP2ANPEPBRD4CYP1A2HIF1A | |
| SCHEMBL17973099 | 0.79 | MMP2 (0.60) | MMP2ANPEPBRD4CYP1A2HIF1A | |
| SCHEMBL13998788 | 0.79 | MMP2 (0.39) | MMP2ANPEP | |
| SCHEMBL8404107 | 0.76 | MMP2 (0.57) | MMP2ANPEPBRD4ALDH1A1CYP19A1 | |
| SCHEMBL8404080 | 0.76 | MMP2 (0.57) | MMP2ANPEPBRD4ALDH1A1CYP19A1 | |
| SCHEMBL8404149 | 0.76 | MMP2 (0.57) | MMP2ANPEPBRD4CYP1A2HIF1A | |
| SCHEMBL3973783 | 0.76 | MMP2 (0.57) | MMP2ANPEPBRD4CYP1A2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512074-B2 | Radiolabeled inhibitors of the amino acid transporters ASCT1 and ASCT2 | THE UNIVERSITY OF MONTANA (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150056138-A1 | Radiolabeled Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 | THE UNIVERSITY OF MONTANA | 2015-02-26 | — | — | US | disclosed |
| US-8895607-B2 | Inhibitors of the amino acid transporters ASCT1 and ASCT2 | THE UNIVERSITY OF MONTANA (US) | 2014-11-25 | — | — | US | disclosed |
| US-20130065935-A1 | Novel Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 | THE UNIVERSITY OF MONTANA | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065935-A1 | Novel Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 | SLC1A2, SLC1A1, SLC1A3 | MMP2 4476/4885ANPEP 476/4885BRD4 4694/4885 |
| US-20150056138-A1 | Radiolabeled Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 | SLC1A2, SLC1A1, SLC1A3 | MMP2 4453/4885ANPEP 439/4885BRD4 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.