Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.57 |
| ▸ | ANPEP | P15144 | 10/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404078 | 1.00 | MMP2 (0.57) | MMP2ANPEPBRD4CYP19A1ALDH1A1 | |
| SCHEMBL8404107 | 1.00 | MMP2 (0.57) | MMP2ANPEPBRD4CYP19A1ALDH1A1 | |
| SCHEMBL201253 | 0.86 | MMP2 (0.57) | MMP2ANPEPBRD4CYP19A1ALDH1A1 | |
| SCHEMBL15083833 | 0.86 | MMP2 (0.57) | MMP2ANPEPBRD4CYP19A1ALDH1A1 | |
| SCHEMBL3973783 | 0.86 | MMP2 (0.57) | MMP2ANPEPBRD4CYP19A1ALDH1A1 | |
| SCHEMBL8401945 | 0.86 | MMP2 (0.57) | MMP2ANPEPBRD4CYP19A1ALDH1A1 | |
| SCHEMBL8404149 | 0.86 | MMP2 (0.57) | MMP2ANPEPBRD4CYP19A1ALDH1A1 | |
| SCHEMBL16300655 | 0.81 | MMP2 (0.39) | MMP2ANPEP | |
| SCHEMBL719489 | 0.80 | PTPN1 (0.52) | MMP2ANPEPBRD4ALDH1A1 | |
| SCHEMBL719488 | 0.80 | PTPN1 (0.52) | MMP2ANPEPBRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5928933-A | SEPARATING RACEMIC MIXTURE BY ENANTIOSELECTIVELY HYDROLYZING THE ESTER OF THE L-ISOMER; CHEMICAL INTERMEDIATE FOR 4-HYDROXYPROLINE | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1999-07-27 | — | — | US | disclosed |