SCHEMBL14770293

SCHEMBL14770293

CCCCCCN(CCCCCC)c1ccc(/C=C/c2ccc(C)s2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INSR P06213 4/20 0.48
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM5 P08912 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRM3 P20309 1/20 0.43
KDM4A O75164 4/20 0.41
KDM2A Q9Y2K7 4/20 0.41
MAPT P10636 4/20 0.39
ATM Q13315 2/20 0.39
KCNH2 Q12809 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
MEN1 O00255 2/20 0.34
NPC1 O15118 2/20 0.34
KMT2A Q03164 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18799270 1.00 INSR (0.48) INSRPTGS1PTGS2CHRM2CHRM4
SCHEMBL18799272 0.94 INSR (0.47) INSRPTGS1PTGS2CHRM2CHRM4
SCHEMBL7719119 0.84 CHRM2 (0.54) INSRCHRM2CHRM4CHRM5CHRM1
SCHEMBL1832514 0.82 CHRM2 (0.55) INSRCHRM2CHRM4CHRM5CHRM1
SCHEMBL5712573 0.82 CHRM2 (0.55) INSRCHRM2CHRM4CHRM5CHRM1
SCHEMBL5712574 0.82 CHRM2 (0.55) INSRCHRM2CHRM4CHRM5CHRM1
SCHEMBL14770327 0.81 INSR (0.44) INSRCHRM2CHRM4CHRM5CHRM1
SCHEMBL13086349 0.81 INSR (0.49) INSRPTGS1PTGS2CHRM2CHRM4
SCHEMBL2604957 0.81 CHRM2 (0.57) INSRCHRM2CHRM4CHRM5CHRM1
SCHEMBL11934288 0.80 INSR (0.46) INSRCHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130065849-A1 BIPHOTONIC PHOTOSENSITIZERS, NANOPARTICLES CONTAINING THE SAME AND THEIR USE AS DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-03-14 US disclosed
US-20130065849-A1 BIPHOTONIC PHOTOSENSITIZERS, NANOPARTICLES CONTAINING THE SAME AND THEIR USE AS DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130065849-A1 BIPHOTONIC PHOTOSENSITIZERS, NANOPARTICLES CONTAINING THE SAME AND THEIR USE AS DRUGS CCNB1, ABCB1, CA6 INSR 3562/4885PTGS1 1767/4885PTGS2 1544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.