SCHEMBL147705

SCHEMBL147705

O=C(O)c1ccc(SSc2ccc(C(=O)O)cn2)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP2C9 P11712 1/20 1.00
HPGD P15428 1/20 1.00
CYP2C19 P33261 1/20 1.00
HSD17B10 Q99714 1/20 1.00
P4HA1 P13674 3/20 0.59
P4HTM Q9NXG6 2/20 0.59
MIF P14174 1/20 0.57
GABRP O00591 1/20 0.55
GABRD O14764 1/20 0.55
GABRA1 P14867 1/20 0.55
GABRB1 P18505 1/20 0.55
GABRG2 P18507 1/20 0.55
GABRB3 P28472 1/20 0.55
GABRA5 P31644 1/20 0.55
GABRA3 P34903 1/20 0.55
GABRA2 P47869 1/20 0.55
GABRB2 P47870 1/20 0.55
GABRA4 P48169 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29693605 1.00 ALDH1A1 (1.00) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL11505192 0.98 ALDH1A1 (0.96) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19
Ammonia Solution, Strong SCHEMBL11504738 0.98 ALDH1A1 (0.96) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19
Hydrogen Sulfide SCHEMBL22616567 0.98 ALDH1A1 (0.96) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19
Ammonia Solution, Strong SCHEMBL11504736 0.98 ALDH1A1 (0.96) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL11504397 0.98 ALDH1A1 (0.96) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL11504865 0.98 ALDH1A1 (0.96) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL11504782 0.98 ALDH1A1 (0.96) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL22616569 0.96 ALDH1A1 (0.92) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL13539393 0.88 ALDH1A1 (0.79) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12419551-B2 Mediation of in vivo analyte signal degradation SENSEONICS, INCORPORATED (US) 2025-09-23 US claimed
WO-2025074986-A1 MODIFIED POLYCARBONATE, METHOD FOR PRODUCING MODIFIED POLYCARBONATE, AND RESIN COMPOSITION 株式会社カネカ 2025-04-10 WO claimed
EP-3965657-B1 MEDIATION OF IN VIVO ANALYTE SIGNAL DEGRADATION SENSEONICS INC (US) 2025-03-05 EP claimed
EP-4493743-A1 GOLD ELECTROPLATING SOLUTION AND ITS USE FOR ELECTRODEPOSITING GOLD WITH AN AGED APPEARANCE Université de Franche-Comté (FR) 2025-01-22 EP claimed
US-20240132955-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS ULTIMA GENOMICS, INC. 2024-04-25 US claimed
EP-4314324-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS Ultima Genomics, Inc. (US) 2024-02-07 EP claimed
WO-2023174871-A1 GOLD ELECTROPLATING SOLUTION AND ITS USE FOR ELECTRODEPOSITING GOLD WITH AN AGED APPEARANCE Université de Franche-Comté (FR) 2023-09-21 WO claimed
CN-116103922-B Sweat-absorbing breathable elastic jean and preparation process thereof 江苏德利恒棉业有限公司 2023-06-20 CN claimed
CN-116103922-A Sweat-absorbing breathable elastic jean and preparation process thereof 江苏德利恒棉业有限公司 2023-05-12 CN claimed
WO-2022212408-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS ULTIMA GENOMICS, INC. (US) 2022-10-06 WO claimed
EP-0782632-A1 A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the Secretary of the Department of Health and Human Services (US) 1997-07-09 EP claimed
WO-1996009406-A9 A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN 1996-05-23 WO claimed
WO-1996009406-A1 A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-03-28 WO claimed
EP-0527186-A4 UNIV ILLINOIS (US) 1995-01-18 EP claimed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP claimed
EP-0464388-A1 Detection assays having chromogenic and nonchromogenic, hypocromogenic, bathochromogenic or hypsochromogenic substrates TECHNICON INSTRUMENTS CORPORATION (a New York corporation) (US) 1992-01-08 EP claimed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO claimed
US-4378364-A DITHIOBIS(PYRIDINE-CARBOXYLIC ACID) TO RELIEVE PAIN, INCREASE APPETITE GRASSETTI DAVIDE R 1983-03-29 US claimed
US-4152439-A 6,6-DITHIODINICOTINIC ACID, ESTER OR ALKALI METAL OR AMMONIUM SALT Grassetti, Davide R. (US) 1979-05-01 US claimed
US-4036709-A ORGANIC DISULFIDE M & T CHEMICALS INC. (US) 1977-07-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12419551-B2 Mediation of in vivo analyte signal degradation SLC2A1, TXN2, SLC2A8 ALDH1A1 323/4885CYP1A2 2625/4885CYP2C9 1518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.