SCHEMBL14770541

SCHEMBL14770541

Cc1ccc2c(c1)Cc1ccccc1N2C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 1/20 0.44
HTR2C P28335 5/20 0.41
HTR2A P28223 5/20 0.41
HRH1 P35367 4/20 0.41
MAOA P21397 1/20 0.39
HSD17B3 P37058 1/20 0.39
SLC6A2 P23975 4/20 0.39
SLC6A4 P31645 4/20 0.39
ADRA2A P08913 3/20 0.39
ADRA2B P18089 3/20 0.39
ADRA2C P18825 3/20 0.39
HTR2B P41595 3/20 0.39
ADRA1A P35348 3/20 0.39
KCNH2 Q12809 2/20 0.39
DRD2 P14416 4/20 0.38
DRD3 P35462 3/20 0.38
DRD1 P21728 3/20 0.38
DRD4 P21917 3/20 0.38
DRD5 P21918 2/20 0.38
HTR1A P08908 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL812617 0.90 PDE5A (0.42) PDE5ASLC6A2SLC6A4ALDH1A1KDM4E
SCHEMBL12841616 0.89 HTR2A (0.45) HTR2CHTR2AHRH1MAOAHSD17B3
Bromide SCHEMBL27751559 0.86 MAOA (0.50) HTR2CHTR2AHRH1MAOASLC6A2
SCHEMBL11978694 0.85 NOTUM (0.44) HTR2CHTR2AHRH1MAOAHSD17B3
SCHEMBL12723261 0.84 MAOA (0.45) HTR2CHTR2AHRH1MAOASLC6A2
SCHEMBL975897 0.84 MAOA (0.52) HTR2CHTR2AHRH1MAOASLC6A2
SCHEMBL29351597 0.84 MAOA (0.52) HTR2CHTR2AHRH1MAOASLC6A2
SCHEMBL13326613 0.83 PDE5A (0.43) PDE5AHSD17B3SLC6A2SLC6A4DRD2
SCHEMBL29735917 0.82 MAOA (0.50) HTR2CHTR2AHRH1MAOASLC6A2
Iodide SCHEMBL11862710 0.82 MAOA (0.50) HTR2CHTR2AHRH1MAOASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074304-A1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING BLUE LIGHT SAMSUNG DISPLAY CO., LTD. (KR) 2024-02-29 US disclosed
US-20240032420-A1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING GREEN LIGHT SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 US disclosed
US-20240032317-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 US disclosed
US-20230380199-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-23 US disclosed
US-20230371364-A1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING BLUE LIGHT SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-16 US disclosed
US-20230371294-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-16 US disclosed
US-20230363195-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-20230345750-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-26 US disclosed
US-20230345751-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-26 US disclosed
US-20230329022-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-12 US disclosed
US-20230329024-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-12 US disclosed
US-20230329028-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-12 US disclosed
CN-112047885-B Gamma- (9-acridine) diazo acetoacetate, gamma- (9-acridine methylene) -beta-keto ester and preparation method thereof 中山大学 2022-05-06 CN disclosed
US-9604972-B2 Nitrogen-containing heteroaromatic ring compound IDEMITSU KOSAN CO., LTD. (JP) 2017-03-28 US disclosed
WO-2015159122-A1 NUCLEIC ACID BASED SENSOR AND METHODS THEREOF NATIONAL CENTRE FOR BIOLOGICAL SCIENCES (IN) 2015-10-22 WO disclosed
US-20150056554-A1 Oxime Ester Photoinitiators CIBA CORPORATION (US) 2015-02-26 US disclosed
US-8940464-B2 Oxime ester photoinitiators BASF SE (DE) 2015-01-27 US disclosed
US-8911921-B2 Oxime ester photoinitiators CIBA CORPORATION (US) 2014-12-16 US disclosed
US-8524425-B2 Oxime ester photoinitiators BASF SE (DE) 2013-09-03 US disclosed
US-20130062597-A1 NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2013-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130062597-A1 NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND TDO2, AHR, NOC2L PDE5A 4446/4885HTR2C 78/4885HTR2A 451/4885
US-20150056554-A1 Oxime Ester Photoinitiators CBR3, CCNE2, CBR1 PDE5A 3020/4885HTR2C 1149/4885HTR2A 1275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.