Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PRKDC | P78527 | 12/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
| ▸ | PTPRF | P10586 | 3/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14770641 | 0.91 | NPC1 (0.39) | PRKDCNPC1MAPTPTPRFPTPN2 | |
| SCHEMBL21946606 | 0.89 | ALOX5 (0.53) | ALOX5PRKDCPRMT5WDR77NPC1 | |
| SCHEMBL22107631 | 0.89 | ALOX5 (0.53) | ALOX5PRKDCPRMT5WDR77NPC1 | |
| SCHEMBL16573892 | 0.88 | ALOX5 (0.50) | ALOX5PRKDCPRMT5WDR77NPC1 | |
| SCHEMBL20715118 | 0.87 | ALOX5 (0.51) | ALOX5PRKDCPRMT5WDR77NPC1 | |
| SCHEMBL17248353 | 0.87 | ALOX5 (0.51) | ALOX5PRKDCPRMT5WDR77NPC1 | |
| SCHEMBL17885403 | 0.86 | ALOX5 (0.48) | ALOX5PRKDCPRMT5WDR77NPC1 | |
| SCHEMBL23433175 | 0.86 | ALOX5 (0.50) | ALOX5PRKDCPRMT5WDR77NPC1 | |
| SCHEMBL14770639 | 0.86 | KDM4E (0.34) | PRKDCNPC1MAPTPTPRFPTPN2 | |
| SCHEMBL23433448 | 0.86 | ALOX5 (0.52) | ALOX5PRKDCPRMT5WDR77NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | TDO2, AHR, NOC2L | ALOX5 1836/4885PRKDC 3941/4885PRMT5 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.