Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30388267 | 0.78 | CYP2C9 (0.37) | CYP3A4CYP2C9CYP2C19POLBMAPT | |
| SCHEMBL11316391 | 0.76 | ALDH1A1 (0.38) | CYP3A4CYP2C9CYP2C19POLBMAPT | |
| SCHEMBL8532180 | 0.75 | POLB (0.40) | CYP3A4CYP2C9CYP2C19POLBMAPT | |
| SCHEMBL1052265 | 0.75 | POLB (0.40) | CYP3A4CYP2C9CYP2C19POLBMAPT | |
| SCHEMBL10040223 | 0.74 | ALDH1A1 (0.38) | CYP3A4CYP2C19MAPTALDH1A1GAA | |
| SCHEMBL14524858 | 0.72 | POLB (0.38) | CYP3A4CYP2C9CYP2C19POLBMAPT | |
| SCHEMBL1051880 | 0.72 | POLB (0.53) | CYP3A4CYP2C9CYP2C19POLBMAPT | |
| SCHEMBL23778988 | 0.72 | L3MBTL1 (0.35) | CYP3A4CYP2C9CYP2C19POLBMAPT | |
| SCHEMBL15162611 | 0.71 | POLB (0.36) | CYP3A4CYP2C9CYP2C19POLBMAPT | |
| SCHEMBL11346348 | 0.71 | L3MBTL1 (0.46) | CYP3A4CYP2C9CYP2C19POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036835-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. (US) | 2013-03-14 | — | — | WO | disclosed |