Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 12/20 | 0.54 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14774781 | 0.94 | CCR5 (0.52) | CCR5PTGER1USP28IDO1AGXT | |
| SCHEMBL14774729 | 0.92 | USP28 (0.51) | CCR5PTGER1USP28MEN1KMT2A | |
| SCHEMBL14774757 | 0.91 | IDO1 (0.51) | CCR5PTGER1IDO1AGXTMAPK14 | |
| SCHEMBL14774706 | 0.86 | SMN1; SMN2 (0.49) | CCR5PTGER1USP28MEN1KMT2A | |
| SCHEMBL14774834 | 0.86 | CCR5 (0.50) | CCR5PTGER1USP28MAPK14MEN1 | |
| SCHEMBL14774660 | 0.84 | PTGER1 (0.57) | PTGER1IDO1AGXTMEN1KMT2A | |
| SCHEMBL14774689 | 0.83 | IDO1 (0.51) | CCR5PTGER1USP28IDO1MEN1 | |
| SCHEMBL3457588 | 0.83 | IDO1 (0.50) | PTGER1IDO1AGXTMAPK14MEN1 | |
| SCHEMBL14774715 | 0.83 | PTGER1 (0.48) | CCR5PTGER1USP28MEN1KMT2A | |
| SCHEMBL5096177 | 0.82 | CCR5 (0.55) | CCR5PTGER1IDO1AGXTMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766344-B1 | EP1 RECEPTOR LIGANDS | ESTEVE LABOR DR (ES) | 2017-05-03 | — | — | EP | disclosed |
| EP-2570125-A1 | Ep1 receptor ligands | Almirall, S.A. (ES) | 2013-03-20 | — | — | EP | disclosed |