SCHEMBL14774641

SCHEMBL14774641

COc1cc([C@@H]2CC(=O)Oc3cc(O)ccc32)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.69
KMT2A Q03164 6/20 0.69
MEN1 O00255 5/20 0.69
MAPT P10636 5/20 0.67
THRB P10828 2/20 0.67
HPGD P15428 3/20 0.64
PTPN1 P18031 1/20 0.57
USP2 O75604 1/20 0.56
CYP19A1 P11511 1/20 0.55
GLA P06280 1/20 0.54
POLB P06746 1/20 0.54
RECQL P46063 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14774755 1.00 ALDH1A1 (0.69) ALDH1A1KMT2AMEN1MAPTTHRB
SCHEMBL24781213 1.00 ALDH1A1 (0.69) ALDH1A1KMT2AMEN1MAPTTHRB
SCHEMBL28225879 0.93 ALDH1A1 (0.69) ALDH1A1KMT2AMEN1MAPTTHRB
SCHEMBL14775862 0.92 ALDH1A1 (0.67) ALDH1A1KMT2AMEN1MAPTTHRB
SCHEMBL14774904 0.92 ALDH1A1 (0.67) ALDH1A1KMT2AMEN1MAPTTHRB
SCHEMBL14781360 0.92 ALDH1A1 (0.67) ALDH1A1KMT2AMEN1MAPTTHRB
SCHEMBL14774891 0.89 ALDH1A1 (0.75) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL14774675 0.89 ALDH1A1 (0.75) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL19760402 0.86 ALDH1A1 (0.60) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL14774931 0.86 MEN1 (0.71) ALDH1A1KMT2AMEN1MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12262725-B2 Improving taste profile of orange juice SYMRISE AG (DE) 2025-04-01 US disclosed
US-20180360086-A1 FOODSTUFF (III) SYMRISE AG (DE) 2018-12-20 US disclosed
EP-3367818-A1 FOODSTUFF (III) Symrise AG (DE) 2018-09-05 EP disclosed
WO-2017071784-A1 FOODSTUFF (III) SYMRISE AG (DE) 2017-05-04 WO disclosed
WO-2017071784-A1 FOODSTUFF (III) SYMRISE AG (DE) 2017-05-04 WO disclosed
US-9131716-B2 Use of neoflavonoids for flavor modification SYMRISE AG (DE) 2015-09-15 US disclosed
US-9131716-B2 Use of neoflavonoids for flavor modification SYMRISE AG (DE) 2015-09-15 US disclosed
US-9131716-B2 Use of neoflavonoids for flavor modification SYMRISE AG (DE) 2015-09-15 US disclosed
EP-2570035-B1 Use of neoflavanoids for modifying taste SYMRISE AG (DE) 2014-06-18 EP disclosed
EP-2570035-B1 Use of neoflavanoids for modifying taste SYMRISE AG (DE) 2014-06-18 EP disclosed
US-20130078192-A1 Use of neoflavonoids for flavor modification SYMRISE AG (DE) 2013-03-28 US disclosed
US-20130078192-A1 Use of neoflavonoids for flavor modification SYMRISE AG (DE) 2013-03-28 US disclosed
US-20130078192-A1 Use of neoflavonoids for flavor modification SYMRISE AG (DE) 2013-03-28 US disclosed
EP-2570035-A1 Use of neoflavanoids for modifying taste Symrise AG (DE) 2013-03-20 EP disclosed
EP-2570035-A1 Use of neoflavanoids for modifying taste Symrise AG (DE) 2013-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130078192-A1 Use of neoflavonoids for flavor modification TAS2R20, TAS2R60, TAS2R50 ALDH1A1 401/4885KMT2A 2978/4885MEN1 1630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.