TAS2R20

Taste receptor type 2 member 20 · P59543 · TAS2R20 on Sugi Atlas →

637 patent compounds predicted against TAS2R20, 547 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Isoproterenol (SCHEMBL4165)	1.00	1/20
Isoproterenol (SCHEMBL4166)	1.00	1/20
Levisoprenaline (SCHEMBL250806)	1.00	1/20
Isoproterenol (SCHEMBL3253794)	1.00	1/20
Isoproterenol (SCHEMBL29386243)	1.00	1/20
Isoproterenol (SCHEMBL29519146)	1.00	1/20
Levisoprenaline (SCHEMBL29620666)	1.00	1/20
Isoproterenol (SCHEMBL7627)	0.97	1/20
Isoproterenol (SCHEMBL1333049)	0.97	1/20
Isoproterenol (SCHEMBL3672791)	0.97	1/20
Levisoprenaline (SCHEMBL4745572)	0.97	1/20
Isoproterenol (SCHEMBL5682030)	0.97	1/20
Isoproterenol (SCHEMBL6151626)	0.97	1/20
Isoproterenol (SCHEMBL9614622)	0.97	1/20
Isoproterenol (SCHEMBL28872988)	0.97	1/20
Isoproterenol (SCHEMBL3669257)	0.93	1/20
Isoproterenol (SCHEMBL28121226)	0.90	1/20
Isoproterenol (SCHEMBL2232971)	0.88	1/20
Isoproterenol (SCHEMBL28106224)	0.88	1/20
Isoproterenol (SCHEMBL28296538)	0.88	1/20

Clinical trials — most relevant to TAS2R20 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical Trial of Efficacy and Safety of Raphamin in the Treatment of Coronavirus Disease 2019 in Outpatients	PHASE3	COMPLETED
Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes	PHASE2	COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Satiation Peptides	PHASE1	COMPLETED
Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY	PHASE1	COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Glucagon-like Peptide-1 and Peptide YY	PHASE1	COMPLETED
TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries	nan	COMPLETED
Vegetables Intake and Polymorphism TAS2R38 Gene by Healthy Adults	nan	COMPLETED
NUTRACORE, Glycaemic Index and Appetite	nan	COMPLETED
Allele-specific Expression of a Bitter Taste Receptor	nan	COMPLETED
Fructose and Glucose and TAS1R2 in Type 1 Diabetes	nan	COMPLETED
The Effect of Lactisole on the Responses to Glucose Solution	nan	UNKNOWN
Flavour Programming: Fruit and Vegetable Palatability	nan	COMPLETED
Study of Taste Deficits	nan	COMPLETED
Sensory Study: Taste and Tongue Biology	nan	COMPLETED
Bitter Taste Receptors in Oropharynx Cancer	nan	UNKNOWN
Genetic Variability in Taste Perception	nan	COMPLETED
Ibuprofen Inhibits Human Sweet Taste	nan	COMPLETED
Sucralose and Lactisole Additions to OGTT in Humans	nan	COMPLETED
A Study of the Function of Hormones Present In Taste Buds	nan	COMPLETED
Gustin Gene Polymorphism and 6-n-propylthiouracil (PROP) Taste	nan	COMPLETED
Factors Affecting Salt Intake in Young Adults	nan	UNKNOWN
CD36 and Human Fat Taste Perception	nan	COMPLETED
The Molecular Basis for a Broad Range of Phenotypes Related to hTAS2R38	nan	COMPLETED
Astringency and Oral Health	nan	COMPLETED
Impacts of Sugar-Sweetened Beverage on Body Weight	nan	COMPLETED
Adaptation Strategies for Coping With the Impact of Sensory Alterations on Eating Behavior in Children With Cancer: A Qualitative Study From the Perspective of Children and Parents	nan	NOT_YET_RECRUITING
The Effect of Artificial Sweeteners on Blood Glucose Response	nan	WITHDRAWN
Gustatory Dysfunction Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy	nan	COMPLETED
Sensitive Periods in Early Flavor Learning	nan	COMPLETED
Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a TAS2R20 binder may also engage these)

Protein	Name	Similarity
Q646A0	—	1.000	Q646A0 →
P0DSN6	—	1.000	P0DSN6 →
Q646G1	—	1.000	Q646G1 →
Q646C2	—	1.000	Q646C2 →
Q646E3	—	1.000	Q646E3 →
Q5Y500	—	1.000	Q5Y500 →
Q645Z7	—	1.000	Q645Z7 →
Q646E1	—	0.999	Q646E1 →
Q5Y4Z8	—	0.999	Q5Y4Z8 →
TAS2R46	Taste receptor type 2 member 46	0.999	landscape →
Q5Y4Y8	—	0.998	Q5Y4Y8 →
TAS2R31	Taste receptor type 2 member 31	0.998	landscape →
Q646C0	—	0.998	Q646C0 →
Q645V4	—	0.998	Q645V4 →
P0DTE0	—	0.998	P0DTE0 →
Q5Y4Y9	—	0.997	Q5Y4Y9 →
Q646E4	—	0.997	Q646E4 →
Q645V3	—	0.997	Q645V3 →
Q646C3	—	0.997	Q646C3 →
Q646A1	—	0.997	Q646A1 →
Q645V7	—	0.997	Q645V7 →
TAS2R30	Taste receptor type 2 member 30	0.997	landscape →
Q645Z6	—	0.997	Q645Z6 →
TAS2R19	Taste receptor type 2 member 19	0.997	landscape →
Q645V6	—	0.996	Q645V6 →
Q646B9	—	0.996	Q646B9 →
Q645T4	—	0.996	Q645T4 →
Q645Z9	—	0.996	Q645Z9 →
Q646C1	—	0.996	Q646C1 →
TAS2R45	Taste receptor type 2 member 45	0.996	landscape →