Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775141 | 1.00 | PKM (0.40) | PKMALDH1A1KMT2AMITFSOS1 | |
| SCHEMBL5535905 | 0.88 | PKM (0.41) | PKMALDH1A1KMT2AMITFSOS1 | |
| SCHEMBL5539492 | 0.88 | PKM (0.41) | PKMALDH1A1KMT2AMITFSOS1 | |
| SCHEMBL5536543 | 0.77 | PKM (0.42) | PKMALDH1A1KMT2AMITFSOS1 | |
| SCHEMBL5536554 | 0.77 | PKM (0.42) | PKMALDH1A1KMT2AMITFSOS1 | |
| SCHEMBL13280888 | 0.75 | PKM (0.40) | PKMALDH1A1KMT2AMITFSOS1 | |
| SCHEMBL5536364 | 0.73 | ALDH1A1 (0.37) | PKMALDH1A1KMT2AMITFSOS1 | |
| SCHEMBL5541968 | 0.73 | ALDH1A1 (0.37) | PKMALDH1A1KMT2AMITFSOS1 | |
| SCHEMBL14562772 | 0.69 | ALDH1A1 (0.44) | PKMALDH1A1KMT2AMITFSOS1 | |
| SCHEMBL14563017 | 0.69 | ALDH1A1 (0.44) | PKMALDH1A1KMT2AMITFSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |