SCHEMBL1477549

SCHEMBL1477549

Oc1ccc2c(O)c(Cl)ccc2c1Cl

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.54
MAPK1 P28482 1/20 0.54
ESR1 P03372 9/20 0.46
ESR2 Q92731 9/20 0.46
TSHR P16473 4/20 0.41
AR P10275 2/20 0.38
DPP4 P27487 1/20 0.37
HSD17B10 Q99714 3/20 0.36
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 1/20 0.35
BRD4 O60885 1/20 0.35
LMNA P02545 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MAPT P10636 1/20 0.35
METAP2 P50579 1/20 0.35
METAP1 P53582 1/20 0.35
HPGD P15428 1/20 0.35
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2368215 0.84 CYP3A4 (0.55) CYP3A4MAPK1ESR1ESR2TSHR
SCHEMBL2477256 0.84 DPP4 (0.46) CYP3A4MAPK1TSHRDPP4HSD17B10
SCHEMBL23191190 0.82 CYP3A4 (0.52) CYP3A4MAPK1ESR1ESR2TSHR
SCHEMBL70542 0.79 CYP3A4 (0.65) CYP3A4MAPK1ESR1ESR2TSHR
SCHEMBL30528041 0.79 CYP3A4 (0.65) CYP3A4MAPK1ESR1ESR2TSHR
SCHEMBL19612295 0.74 IDO1 (0.46) CYP3A4ESR1ESR2TSHRAR
SCHEMBL5173101 0.74 MAOB (0.45) CYP3A4MAPK1ESR1ESR2HSD17B10
SCHEMBL136940 0.71 CYP3A4 (1.00) CYP3A4MAPK1ESR1ESR2TSHR
SCHEMBL6349819 0.71 CYP3A4 (0.52) CYP3A4MAPK1TSHRDPP4HSD17B10
SCHEMBL7743436 0.69 CYP3A4 (0.75) CYP3A4MAPK1ESR1ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5151458-A Molding materials for liquid crystal resins BAYER AKTIENGESELLSCHAFT (DE) 1992-09-29 US claimed
US-5143956-A Blends with low molecular weight liquid crystals BAYER AKTIENGESELLSCHAFT (DE) 1992-09-01 US claimed
US-5102935-A With low molecular weight, liquid crystalline esters and/or ester amides BAYER AKTIENGESELLSCHAFT (DE) 1992-04-07 US claimed
EP-0464351-A2 Polycarbonate, polyestercarbonate and polyester moulding compositions with high melt flow BAYER AG (DE) 1992-01-08 EP claimed
EP-0444295-A1 Low-viscosity polyamide mouldings BAYER AG (DE) 1991-09-04 EP claimed
EP-0444292-A2 Easy fluoring polyamide moulding compositions BAYER AG (DE) 1991-09-04 EP claimed
EP-0398052-A2 Low-viscosity polyarylene sulfide mouldings BAYER AG (DE) 1990-11-22 EP claimed
EP-0359037-A2 Low-viscosity polyamide mouldings and mixtures BAYER AG (DE) 1990-03-21 EP claimed
US-8496616-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-30 US disclosed
EP-1991286-B1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENT LTD (BB) 2012-12-26 EP disclosed
US-20120220932-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-08-30 US disclosed
US-8187492-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-05-29 US disclosed
US-20110092999-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-04-21 US disclosed
US-7914485-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-29 US disclosed
EP-0141320-B1 THERMOTROPIC AROMATIC POLYESTERS WITH HIGH STIFFNESS, PROCESS FOR THEIR PRODUCTION AND THEIR USE IN THE PRODUCTION OF MOULDED ARTICLES, FILAMENTS, FIBRES AND FILMS BAYER AG (DE) 1987-10-07 EP disclosed
US-4599395-A Thermotropic, aromatic polyesters having good mechanical strength, containing sulfonic acid groups or metal sulfonate groups a process for the production thereof BAYER AKTIENGESELLSCHAFT (DE) 1986-07-08 US disclosed
EP-0141320-A2 Thermotropic aromatic polyesters with high stiffness, process for their production and their use in the production of moulded articles, filaments, fibres and films BAYER AG (DE) 1985-05-15 EP disclosed
EP-0024499-B1 BIAXIALLY ORIENTED WHOLLY AROMATIC POLYESTER FILM AND PROCESS FOR PRODUCING SAME TEIJIN LIMITED (JP) 1984-03-07 EP disclosed
US-4333907-A Biaxially oriented wholly aromatic polyester film TEITIN LIMITED (JP) 1982-06-08 US disclosed
EP-0024499-A1 Biaxially oriented wholly aromatic polyester film and process for producing same TEIJIN LIMITED (JP) 1981-03-11 EP disclosed