Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 7/20 | 0.76 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.76 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALB | P02768 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | GALK1 | P51570 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43382 | 1.00 | CYP2C9 (0.76) | CYP2C9NR1I2NR3C1ADRA1AKCNH2 | |
| Phenprocoumon SCHEMBL28142123 | 0.90 | CYP2C9 (0.79) | CYP2C9NR1I2NR3C1ADRA1AKCNH2 | |
| SCHEMBL1479347 | 0.88 | CYP2C9 (0.73) | CYP2C9NR1I2NR3C1ADRA1AKCNH2 | |
| SCHEMBL20806 | 0.88 | CYP2C9 (0.73) | CYP2C9NR1I2NR3C1ADRA1AKCNH2 | |
| SCHEMBL136434 | 0.88 | CYP2C9 (0.73) | CYP2C9NR1I2NR3C1ADRA1AKCNH2 | |
| Acenocoumarol SCHEMBL27497093 | 0.86 | CYP2C9 (1.00) | CYP2C9NR1I2NR3C1ADRA1AKCNH2 | |
| Acenocoumarol SCHEMBL33543 | 0.86 | CYP2C9 (1.00) | CYP2C9NR1I2NR3C1ADRA1AKCNH2 | |
| Acenocoumarol SCHEMBL29454369 | 0.86 | CYP2C9 (1.00) | CYP2C9NR1I2NR3C1ADRA1AKCNH2 | |
| Acenocoumarol SCHEMBL14662100 | 0.85 | CYP2C9 (0.98) | CYP2C9NR1I2NR3C1ADRA1AKCNH2 | |
| SCHEMBL1477912 | 0.84 | CYP2C9 (0.63) | CYP2C9NR1I2NR3C1ADRA1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860158-B1 | Particles comprising a substrate and an anion-binding layer | MERCK PATENT GMBH (DE) | 2013-12-04 | — | — | EP | disclosed |
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7914893-B2 | Particles comprising an anion-binding layer containing anion-forming organic active compounds, and method of making and using thereof | MERCK PATENT GMBH (DE) | 2011-03-29 | — | — | US | disclosed |
| US-20100292183-A1 | TETRACYCLINE AND USES THEREOF | PLAXGEN, INC. | 2010-11-18 | — | — | US | disclosed |
| US-20100292183-A1 | TETRACYCLINE AND USES THEREOF | PLAXGEN, INC. | 2010-11-18 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20070275244-A1 | Particles | MERCK PATENT GMBH | 2007-11-29 | — | — | US | disclosed |
| EP-1860158-A2 | Particles comprising a substrate and an anion-binding layer | MERCK PATENT GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292183-A1 | TETRACYCLINE AND USES THEREOF | TET1, TET3, TNNT2 | CYP2C9 577/4885NR1I2 1794/4885NR3C1 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.