Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 9/20 | 0.63 |
| ▸ | ALB | P02768 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.60 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20806 | 0.92 | CYP2C9 (0.73) | CYP2C9ALBHSD17B10ALDH1A1KDM4E | |
| SCHEMBL1479347 | 0.92 | CYP2C9 (0.73) | CYP2C9ALBHSD17B10ALDH1A1KDM4E | |
| SCHEMBL136434 | 0.92 | CYP2C9 (0.73) | CYP2C9ALBHSD17B10ALDH1A1KDM4E | |
| Phosphoric Acid SCHEMBL28278851 | 0.86 | CYP2C9 (0.66) | CYP2C9ALBHSD17B10ALDH1A1KDM4E | |
| Coumachlor SCHEMBL433455 | 0.85 | CYP2C9 (0.84) | CYP2C9ALBHSD17B10ALDH1A1KDM4E | |
| Coumachlor SCHEMBL30930052 | 0.85 | CYP2C9 (0.84) | CYP2C9ALBHSD17B10ALDH1A1KDM4E | |
| SCHEMBL43382 | 0.84 | CYP2C9 (0.76) | CYP2C9ALBHSD17B10ALDH1A1KDM4E | |
| SCHEMBL1477562 | 0.84 | CYP2C9 (0.76) | CYP2C9ALBHSD17B10ALDH1A1KDM4E | |
| SCHEMBL1478281 | 0.80 | CYP2C9 (0.58) | CYP2C9ALBHSD17B10ALDH1A1KDM4E | |
| SCHEMBL29489752 | 0.80 | CYP2C9 (0.58) | CYP2C9ALBHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860158-B1 | Particles comprising a substrate and an anion-binding layer | MERCK PATENT GMBH (DE) | 2013-12-04 | — | — | EP | disclosed |
| US-7914893-B2 | Particles comprising an anion-binding layer containing anion-forming organic active compounds, and method of making and using thereof | MERCK PATENT GMBH (DE) | 2011-03-29 | — | — | US | disclosed |
| US-20070275244-A1 | Particles | MERCK PATENT GMBH | 2007-11-29 | — | — | US | disclosed |
| EP-1860158-A2 | Particles comprising a substrate and an anion-binding layer | MERCK PATENT GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| US-20060276339-A1 | Methods and compositions for increasing the efficacy of biologically-active ingredients | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276339-A1 | Methods and compositions for increasing the efficacy of biologically-active ingredients | ENPP1, ENPP3, SMPD1 | CYP2C9 1687/4885ALB 4278/4885HSD17B10 2715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.