Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164002 | 0.87 | PTGER4 (0.55) | PTGER4PTGER3PTGER2 | |
| SCHEMBL14775810 | 0.85 | PTGER4 (0.46) | PTGER4PTGER3PTGER2 | |
| SCHEMBL14775833 | 0.83 | PTGER4 (0.58) | P2RX7PTGER4PTGER3ALDH1A1PTGER2 | |
| SCHEMBL14775796 | 0.81 | PTGER4 (0.47) | P2RX7PTGER4PTGER3KDM4EALDH1A1 | |
| SCHEMBL4990309 | 0.80 | PTGER4 (0.40) | PTGER4PTGER3PTGER2 | |
| SCHEMBL14775668 | 0.78 | PTGER4 (0.42) | P2RX7PTGER4PTGER3KDM4EPTGER2 | |
| SCHEMBL4993850 | 0.78 | PTGER4 (0.49) | P2RX7PTGER4PTGER3PTGER2 | |
| SCHEMBL14781402 | 0.75 | FAAH (0.39) | PTGER4ALDH1A1 | |
| SCHEMBL14775664 | 0.74 | PTGER4 (0.52) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4994025 | 0.74 | PTGER4 (0.47) | PTGER4PTGER3ALDH1A1PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503984-B1 | 8-AZAPROSTAGLANDIN ANALOGS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | ALLERGAN INC (US) | 2013-03-20 | — | — | EP | claimed |