Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.58 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.58 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160079 | 0.88 | PTGER4 (0.73) | PTGER4PTGER3PTGER2 | |
| SCHEMBL14775668 | 0.87 | PTGER4 (0.42) | PTGER4PTGER3PTGER2P2RX7 | |
| SCHEMBL14775810 | 0.87 | PTGER4 (0.46) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6710472 | 0.86 | PTGER4 (0.79) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6674789 | 0.86 | PTGER4 (0.79) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4990309 | 0.84 | PTGER4 (0.40) | PTGER4PTGER3PTGER2 | |
| SCHEMBL14775797 | 0.83 | P2RX7 (0.43) | PTGER4PTGER3PTGER2P2RX7ALDH1A1 | |
| SCHEMBL6711603 | 0.82 | PTGER4 (0.59) | PTGER4PTGER3PTGER2P2RX7ALDH1A1 | |
| SCHEMBL6694775 | 0.82 | PTGER4 (0.59) | PTGER4PTGER3PTGER2P2RX7ALDH1A1 | |
| SCHEMBL6713022 | 0.78 | PTGER4 (0.50) | PTGER4PTGER3PTGER2P2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503984-B1 | 8-AZAPROSTAGLANDIN ANALOGS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | ALLERGAN INC (US) | 2013-03-20 | — | — | EP | claimed |