Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 3/20 | 0.32 |
| ▸ | LDHB | P07195 | 3/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.31 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775713 | 0.83 | PKM (0.32) | LMNAALDH1A1HTTMEN1GAA | |
| SCHEMBL14775733 | 0.76 | CDK2 (0.40) | HPGDLMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL1658622 | 0.73 | COMT (0.42) | HPGDLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL12082517 | 0.70 | MEN1 (0.32) | HPGDLMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL1655889 | 0.68 | PKM (0.42) | HPGDLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL12082330 | 0.68 | MEN1 (0.36) | HPGDLMNAALDH1A1RAB9AMAPT | |
| SCHEMBL12717681 | 0.68 | POLB (0.36) | HPGDLMNAALDH1A1HTTMAPT | |
| SCHEMBL12082570 | 0.66 | PKM (0.40) | HPGDLMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL12717517 | 0.65 | S1PR1 (0.36) | HPGDLMNAMAPTMEN1GAA | |
| SCHEMBL27520450 | 0.63 | KMT2A (0.47) | LMNAALDH1A1TAAR1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305633-B1 | Catechol derivative and its use | KISSEI PHARMACEUTICAL (JP) | 2013-03-20 | — | — | EP | claimed |