Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1658622 | 0.83 | COMT (0.42) | PTGDR2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1655889 | 0.83 | PKM (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL12082517 | 0.81 | MEN1 (0.32) | ALDH1A1TDP1SMN1; SMN2GPR35HDAC1 | |
| SCHEMBL12082320 | 0.78 | CDK2 (0.52) | CDK2ALDH1A1TDP1SMN1; SMN2GPR35 | |
| SCHEMBL14775858 | 0.76 | HPGD (0.34) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL12717681 | 0.76 | POLB (0.36) | ALDH1A1TDP1GPR35MEN1KMT2A | |
| SCHEMBL14775713 | 0.75 | PKM (0.32) | PTGDR2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL14775633 | 0.73 | FTO (0.44) | CDK2ALDH1A1KMT2AHPGDCOMT | |
| SCHEMBL12082255 | 0.73 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL12082269 | 0.73 | MAPT (0.36) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305633-B1 | Catechol derivative and its use | KISSEI PHARMACEUTICAL (JP) | 2013-03-20 | — | — | EP | claimed |