Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL14778470 | 0.98 | ALDH1A1 (0.49) | ALDH1A1APAF1RAD52NPSR1RGS12 | |
| Iodide SCHEMBL14779128 | 0.98 | ALDH1A1 (0.49) | ALDH1A1APAF1RAD52NPSR1RGS12 | |
| Iodide SCHEMBL14778344 | 0.98 | ALDH1A1 (0.49) | ALDH1A1APAF1RAD52NPSR1RGS12 | |
| Hydrochloric Acid SCHEMBL14777890 | 0.97 | ALDH1A1 (0.50) | ALDH1A1APAF1RAD52NPSR1RGS12 | |
| Bromide SCHEMBL14779145 | 0.95 | ALDH1A1 (0.49) | ALDH1A1APAF1RAD52NPSR1RGS12 | |
| Hydrochloric Acid SCHEMBL14778467 | 0.95 | ALDH1A1 (0.52) | ALDH1A1APAF1RAD52NPSR1RGS12 | |
| Hydrochloric Acid SCHEMBL14777818 | 0.95 | ALDH1A1 (0.52) | ALDH1A1APAF1RAD52NPSR1RGS12 | |
| SCHEMBL13227444 | 0.90 | ALDH1A1 (0.54) | ALDH1A1APAF1RAD52NPSR1RGS12 | |
| Iodide SCHEMBL14778925 | 0.89 | XDH (0.52) | ALDH1A1APAF1RAD52NPSR1RGS12 | |
| Bromide SCHEMBL14777635 | 0.85 | XDH (0.52) | ALDH1A1APAF1RAD52NPSR1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658842-B2 | Process for producing ethylene glycol catalyzed by ionic liquid | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2014-02-25 | — | — | US | disclosed |
| US-20130072727-A1 | PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072727-A1 | PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID | AGL, ALKBH3, ELL | ACHE 3247/4885ALDH1A1 1764/4885APAF1 3785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.