Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14779118 | 0.96 | ALDH1A1 (0.38) | ALDH1A1CYP2D6CYP1A2SMN1; SMN2CHRM2 | |
| SCHEMBL14778433 | 0.92 | CYP2D6 (0.37) | ALDH1A1CYP2D6CYP1A2SMN1; SMN2CHRM2 | |
| SCHEMBL28012898 | 0.85 | ALDH1A1 (0.40) | ALDH1A1CYP2D6CYP1A2SMN1; SMN2CHRM2 | |
| SCHEMBL7389158 | 0.81 | TAAR1 (0.33) | — | |
| SCHEMBL3895160 | 0.76 | CYP2D6 (0.35) | ALDH1A1CYP2D6CYP1A2SMN1; SMN2CHRM2 | |
| SCHEMBL28013476 | 0.76 | ALDH1A1 (0.38) | ALDH1A1CYP2D6CYP1A2SMN1; SMN2CHRM2 | |
| SCHEMBL9341766 | 0.76 | CYP1A2 (0.39) | ALDH1A1CYP2D6CYP1A2SMN1; SMN2CHRM2 | |
| SCHEMBL11779255 | 0.76 | CYP2D6 (0.39) | ALDH1A1CYP2D6CYP1A2CHRM2CHRM4 | |
| SCHEMBL14778850 | 0.76 | TSHR (0.39) | ALDH1A1CYP2D6CYP1A2SMN1; SMN2CHRM2 | |
| SCHEMBL747102 | 0.76 | OPRM1 (0.33) | ALDH1A1CYP1A2OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072648-A1 | SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-21 | — | — | US | disclosed |