Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL14779129 | 1.00 | CES1 (0.36) | CES1CDC25AMPOALDH1A1KDM4E | |
| Iodide SCHEMBL14778471 | 1.00 | CES1 (0.36) | CES1CDC25AMPOALDH1A1KDM4E | |
| Iodide SCHEMBL14777829 | 0.98 | ALDH1A1 (0.35) | CES1CDC25AMPOALDH1A1KDM4E | |
| Bromide SCHEMBL14779146 | 0.97 | CES1 (0.36) | CES1CDC25AMPOALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL14778468 | 0.97 | CES1 (0.36) | CES1CDC25AMPOALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL14777819 | 0.97 | CES1 (0.36) | CES1CDC25AMPOALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL14777891 | 0.95 | ALDH1A1 (0.35) | CES1CDC25AMPOALDH1A1KDM4E | |
| Iodide SCHEMBL14778927 | 0.86 | ALDH1A1 (0.38) | CES1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL19411245 | 0.84 | ALDH1A1 (0.39) | CES1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL21049605 | 0.83 | CDC25A (0.51) | CES1CDC25AALDH1A1KDM4EALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658842-B2 | Process for producing ethylene glycol catalyzed by ionic liquid | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2014-02-25 | — | — | US | disclosed |
| US-20130072727-A1 | PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072727-A1 | PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID | AGL, ALKBH3, ELL | CHRM1 2452/4885CES1 1331/4885CDC25A 2089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.