Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.32 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.32 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.32 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL14778471 | 0.97 | CES1 (0.36) | CES1CDC25AMPOALDH1A1KDM4E | |
| Iodide SCHEMBL14779129 | 0.97 | CES1 (0.36) | CES1CDC25AMPOALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL14777819 | 0.97 | CES1 (0.36) | CES1CDC25AMPOALDH1A1KDM4E | |
| Iodide SCHEMBL14778346 | 0.97 | CES1 (0.36) | CES1CDC25AMPOALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL14778468 | 0.97 | CES1 (0.36) | CES1CDC25AMPOALDH1A1KDM4E | |
| Iodide SCHEMBL14777829 | 0.95 | ALDH1A1 (0.35) | CES1CDC25AMPOALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL14777891 | 0.95 | ALDH1A1 (0.35) | CES1CDC25AMPOALDH1A1KDM4E | |
| Bromide SCHEMBL14777636 | 0.86 | ALDH1A1 (0.38) | CES1ALDH1A1KDM4EGAAMAPT | |
| Bromide SCHEMBL14777972 | 0.85 | ALDH1A1 (0.36) | CES1CDC25AMPOALDH1A1KDM4E | |
| Bromide SCHEMBL14778180 | 0.85 | ALDH1A1 (0.36) | CES1CDC25AMPOALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658842-B2 | Process for producing ethylene glycol catalyzed by ionic liquid | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2014-02-25 | — | — | US | disclosed |
| US-20130072727-A1 | PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072727-A1 | PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID | AGL, ALKBH3, ELL | CHRM2 2537/4885HTR1A 4213/4885ADRA2A 4793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.