Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 9/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14778045 | 1.00 | TSHR (0.38) | TSHRTHRBGGPS1SMPD1ADRB2 | |
| SCHEMBL14777506 | 0.98 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1ADRB2 | |
| SCHEMBL14778033 | 0.98 | ADRB2 (0.36) | TSHRTHRBGGPS1SMPD1ADRB2 | |
| SCHEMBL14779371 | 0.95 | ADRB2 (0.38) | TSHRTHRBGGPS1SMPD1ADRB2 | |
| SCHEMBL14779386 | 0.93 | TSHR (0.36) | TSHRTHRBGGPS1SMPD1ADRB2 | |
| SCHEMBL14779511 | 0.93 | TSHR (0.36) | TSHRTHRBGGPS1SMPD1ADRB2 | |
| SCHEMBL14780133 | 0.93 | TSHR (0.36) | TSHRTHRBGGPS1SMPD1ADRB2 | |
| SCHEMBL29555246 | 0.93 | THRB (0.40) | TSHRTHRBGGPS1LPAR1LPAR3 | |
| SCHEMBL14779089 | 0.93 | ADRB2 (0.39) | TSHRTHRBADRB2ADRB1ADRB3 | |
| SCHEMBL14779108 | 0.91 | CYP3A4 (0.36) | TSHRTHRBGGPS1SMPD1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072648-A1 | SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-21 | — | — | US | disclosed |