Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14778741 | 0.96 | TSHR (0.41) | TSHRMAPK1SMN1; SMN2L3MBTL1MAOA | |
| SCHEMBL14778250 | 0.92 | TSHR (0.46) | TSHRMAPK1SMN1; SMN2L3MBTL1MAOA | |
| SCHEMBL2286730 | 0.80 | KDM1A (0.42) | TSHRMAPK1SMN1; SMN2L3MBTL1MAOA | |
| SCHEMBL14777801 | 0.78 | GRIN1 (0.44) | TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL14778815 | 0.78 | MAOA (0.43) | L3MBTL1MAOAMAOBKDM1A | |
| SCHEMBL10763758 | 0.78 | ALDH1A1 (0.42) | TSHRMAPK1SMN1; SMN2L3MBTL1MAOA | |
| SCHEMBL2280968 | 0.76 | TSHR (0.44) | TSHRMAPK1SMN1; SMN2L3MBTL1MAOA | |
| SCHEMBL14778102 | 0.76 | TSHR (0.40) | TSHRMAPK1SMN1; SMN2L3MBTL1MAOA | |
| SCHEMBL6319516 | 0.74 | MAPK1 (0.41) | TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL14778149 | 0.74 | MAOA (0.41) | TSHRMAPK1MAOAMAOBOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072648-A1 | SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-21 | — | — | US | disclosed |