SCHEMBL14779147

SCHEMBL14779147

CN(C)C(=O)[C@@H](NC(=O)O)C(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDF Q9HBH1 7/20 0.51
CNR2 P34972 3/20 0.34
TUBB1 Q9H4B7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15736879 0.80 PDF (0.37) PDFTUBB1
SCHEMBL1219001 0.80 PDF (0.37) PDF
SCHEMBL27145161 0.77 CNR2 (0.36) PDFCNR2
SCHEMBL21543027 0.77 CNR2 (0.36) PDFCNR2
SCHEMBL2784044 0.77 CNR2 (0.36) PDFCNR2
SCHEMBL883447 0.77 CA2 (0.43) PDFCNR2
SCHEMBL8357912 0.77 CA2 (0.43) PDFCNR2
SCHEMBL3216755 0.76 CA1 (0.46) PDF
SCHEMBL12866689 0.76 CA1 (0.46) PDF
SCHEMBL7409342 0.74 PDF (0.41) PDF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130072467-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED 2013-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130072467-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND ESRRA, ESRRB, ESR2 PDF 2488/4885CNR2 1542/4885TUBB1 1936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.