Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812916 | 0.97 | LMNA (0.36) | LMNA | |
| SCHEMBL5427759 | 0.97 | LMNA (0.36) | LMNA | |
| SCHEMBL6688844 | 0.90 | — | — | |
| SCHEMBL6678872 | 0.79 | TSHR (0.33) | — | |
| SCHEMBL15851491 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL20991036 | 0.77 | TSHR (0.30) | — | |
| SCHEMBL12050299 | 0.73 | TSHR (0.38) | — | |
| SCHEMBL64068 | 0.71 | LMNA (0.33) | LMNA | |
| SCHEMBL7758494 | 0.71 | LMNA (0.33) | LMNA | |
| SCHEMBL19256904 | 0.71 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130073015-A1 | METHODS AND DEVICES FOR NON-INVASIVE CEREBRAL AND SYSTEMIC COOLING ALTERNATING LIQUID MIST/GAS FOR INDUCTION AND GAS FOR MAINTENANCE | BRAINCOOL AB (SE) | 2013-03-21 | — | — | US | disclosed |