SCHEMBL812916

SCHEMBL812916

CCC(F)(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5427759 1.00 LMNA (0.36) LMNATHRB
SCHEMBL14780252 0.97 LMNA (0.32) LMNA
SCHEMBL6688844 0.88
SCHEMBL6678872 0.77 TSHR (0.33)
SCHEMBL15851491 0.77 TSHR (0.32)
SCHEMBL20991036 0.74 TSHR (0.30)
SCHEMBL13007703 0.73 LMNA (0.38) LMNATHRB
SCHEMBL8737652 0.73 LMNA (0.38) LMNATHRB
SCHEMBL226215 0.73 LMNA (0.38) LMNATHRB
SCHEMBL20604027 0.73 CA2 (0.39) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1514884-B1 Block copolymer comprising a vinyllactam block, cosmetic composition and use of this polymer in cosmetics OREAL (FR) 2009-08-26 EP claimed
US-8748501-B2 Polyurethane foam composition and polyurethane foam prepared using same SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-06-10 US disclosed
US-8053484-B2 Composition for polyurethane foam and polyurethane foam prepared therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-11-08 US disclosed
US-20110054052-A1 POLYURETHANE FOAM COMPOSITION AND POLYURETHANE FOAM PREPARED USING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-03-03 US disclosed
US-20100166685-A1 NOVEL BLOCK POLYMERS, COMPOSITIONS COMPRISING THEM, AND TREATMENT METHODS L'OREAL S.A. 2010-07-01 US disclosed
US-20100113635-A1 COMPOSITION FOR POLYURETHANE FOAM AND POLYURETHANE FOAM PREPARED THEREFROM SAMSUNG ELECTRONICS CO., LTD (KR) 2010-05-06 US disclosed
US-20080181859-A1 Novel block (Co)polymers, compositions containing them, method of treatment and method of preparation L'OREAL S.A. (FR) 2008-07-31 US disclosed
US-20080175804-A1 Novel block polymers, compositions comprising them, and treatment methods L'OREAL S.A. (FR) 2008-07-24 US disclosed
US-20070098664-A1 Cosmetic application of rod-coil copolymers L'OREAL (FR) 2007-05-03 US disclosed
US-20050288410-A1 Copolymer functionalized with an iodine atom, composition comprising it and treatment process L'OREAL S.A. (FR) 2005-12-29 US disclosed
US-5318996-A Blowing with mixture of water, chlorodifluoromethane dichlorofluoroethane and perfluorinated hydrocarbons BASF CORPORATION (US) 1994-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080181859-A1 Novel block (Co)polymers, compositions containing them, method of treatment and method of preparation XRCC5, TBCB, ERCC5 LMNA 571/4885THRB 831/4885
US-20080175804-A1 Novel block polymers, compositions comprising them, and treatment methods RAD52, C1R, LTB4R2 LMNA 2915/4885THRB 2310/4885
US-20070098664-A1 Cosmetic application of rod-coil copolymers COIL, CRYAB, CRYZ LMNA 1519/4885THRB 399/4885
US-20100166685-A1 NOVEL BLOCK POLYMERS, COMPOSITIONS COMPRISING THEM, AND TREATMENT METHODS RAD52, C1R, LTB4R2 LMNA 2915/4885THRB 2310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.