Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 5/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | PI4KA | P42356 | 2/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14779867 | 0.88 | TSHR (0.64) | CDK2CYP1A2TSHRRECQLCDK1 | |
| SCHEMBL14779864 | 0.88 | TSHR (0.64) | CDK2CYP1A2TSHRRECQLCDK1 | |
| SCHEMBL14779911 | 0.84 | CDK2 (0.59) | CDK2CYP1A2TSHRRECQLCDK1 | |
| SCHEMBL14780099 | 0.84 | CDK2 (0.61) | CDK2CYP1A2TSHRRECQLCDK1 | |
| SCHEMBL14780251 | 0.84 | CDK2 (0.55) | CDK2CYP1A2TSHRRECQLCDK1 | |
| SCHEMBL14780256 | 0.83 | CDK2 (0.53) | CDK2CYP1A2TSHRRECQLCDK1 | |
| SCHEMBL14779615 | 0.82 | CDK2 (0.59) | CDK2CYP1A2TSHRRECQLCDK1 | |
| SCHEMBL14779334 | 0.82 | CDK2 (0.59) | CDK2CYP1A2TSHRRECQLCDK1 | |
| SCHEMBL14780330 | 0.77 | CDK2 (0.47) | CDK2CYP1A2TSHRRECQLCDK1 | |
| SCHEMBL6577280 | 0.76 | CYP1A2 (0.36) | CDK2CYP1A2TSHRPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072506-A1 | 6,8-DISUBSTITUTED PURINE COMPOSITIONS | ZAHAJSKA LENKA (CZ) | 2013-03-21 | — | — | US | claimed |
| EP-2755977-A1 | 6, 8- DISUBSTITUTED PURINE COMPOSITIONS AND THEIR PHARMACEUTICAL AND COSMETIC USE | Univerzita Palackého v Olomouci (CZ) | 2014-07-23 | — | — | EP | disclosed |
| US-20130072506-A1 | 6,8-DISUBSTITUTED PURINE COMPOSITIONS | ZAHAJSKA LENKA (CZ) | 2013-03-21 | — | — | US | disclosed |
| WO-2013037333-A1 | 6, 8- DISUBSTITUTED PURINE COMPOSITIONS AND THEIR PHARMACEUTICAL AND COSMETIC USE | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2013-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072506-A1 | 6,8-DISUBSTITUTED PURINE COMPOSITIONS | UNG, PNP, UMPS | CDK2 255/4885CYP1A2 1398/4885TSHR 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.