Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 4/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.34 |
| ▸ | PNP | P00491 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3802729 | 0.87 | TSHR (0.40) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL14780258 | 0.76 | CDK2 (0.61) | CYP1A2CDK2NUDT1PI4KAPI4K2B | |
| SCHEMBL5667619 | 0.72 | ADORA2A (0.43) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL4455866 | 0.72 | PI4KA (0.38) | CYP1A2CDK2NUDT1ADORA2AADORA1 | |
| SCHEMBL6141622 | 0.70 | PI4KA (0.35) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL108321 | 0.69 | LTB4R (0.55) | PI4KAPI4K2BPI4K2API4KBPNP | |
| SCHEMBL320848 | 0.69 | NUDT1 (0.43) | CYP1A2NUDT1ADORA2AADORA1PI4KA | |
| SCHEMBL42314 | 0.68 | ADORA2A (0.66) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL29400753 | 0.68 | ADORA2A (0.66) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL14779867 | 0.68 | TSHR (0.64) | CYP1A2CDK2NUDT1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478000-A | PRETREATMENT SOAKING IN BENZYLADENINE | PLANT RESOURCES INSTITUTE (US) | 1984-10-23 | — | — | US | claimed |
| EP-0584068-B2 | METHOD AND COMPOSITION FOR AMELIORATING THE ADVERSE EFFECTS OF AGING | SENETEK PLC (US) | 2004-04-28 | — | — | EP | disclosed |
| EP-0584068-B1 | METHOD AND COMPOSITION FOR AMELIORATING THE ADVERSE EFFECTS OF AGING | SENETEK PLC (US) | 1999-10-06 | — | — | EP | disclosed |
| EP-0584068-A4 | — | — | 1994-04-06 | — | — | EP | disclosed |
| EP-0584068-A1 | METHOD AND COMPOSITION FOR AMELIORATING THE ADVERSE EFFECTS OF AGING | SENETEK, PLC (US) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992020341-A1 | METHOD AND COMPOSITION FOR AMELIORATING THE ADVERSE EFFECTS OF AGING | SENETEK, PLC (US) | 1992-11-26 | — | — | WO | disclosed |
| US-4478000-A | PRETREATMENT SOAKING IN BENZYLADENINE | PLANT RESOURCES INSTITUTE (US) | 1984-10-23 | — | — | US | disclosed |