SCHEMBL14780280

SCHEMBL14780280

CC(C)C(C)OS(=O)(=O)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
ALDH1A1 P00352 1/20 0.31
CXCR2 P25025 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14779233 0.90 CA1 (0.43) CA1CA2CA9ALDH1A1CXCR2
SCHEMBL14780351 0.85 CA1 (0.35) CA1CA2CA9ALDH1A1CXCR2
SCHEMBL14779315 0.84 CA1 (0.31) CA1CA2CA9
SCHEMBL21178830 0.83 CA1 (0.33) CA1CA2CA9
SCHEMBL14779457 0.83 CA1 (0.33) CA1CA2CA9
SCHEMBL14780033 0.82 CA1 (0.30) CA1CA2CA9
SCHEMBL575704 0.79 CA1 (0.33) CA1CA2CA9ALDH1A1CXCR2
SCHEMBL778573 0.79 ALDH1A1 (0.46) CA1CA2CA9ALDH1A1CXCR2
SCHEMBL28139904 0.78 CA1 (0.34) CA1CA2CA9
SCHEMBL13047233 0.78 ALDH1A1 (0.35) CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024125626-A1 NITROGENOUS COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) 2024-06-20 WO disclosed
US-20220177446-A1 ALKYNE COMPOUNDS AS IRAK INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF Eternity Bioscience Inc. 2022-06-09 US disclosed
WO-2019000237-A1 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR MERCK SHARP & DOHME CORP. (US) 2019-01-03 WO disclosed
EP-2863469-B1 NONAQUEOUS ELECTROLYTE SECONDARY CELL AND METHOD FOR USING SAME MITSUBISHI CHEM CORP (JP) 2017-11-22 EP disclosed
US-9240614-B2 Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES, LTD. (JP) 2016-01-19 US disclosed
EP-2863469-A1 NONAQUEOUS ELECTROLYTE SECONDARY CELL AND METHOD FOR USING SAME Mitsubishi Chemical Corporation (JP) 2015-04-22 EP disclosed
EP-2579377-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES (JP) 2014-09-03 EP disclosed
EP-2579377-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ube Industries, Ltd. (JP) 2013-04-10 EP disclosed
US-20130071733-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES, LTD. (JP) 2013-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220177446-A1 ALKYNE COMPOUNDS AS IRAK INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF IRAK2, IRAK3, IRAK4 CA1 4798/4885CA2 4670/4885CA9 4612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.