SCHEMBL778573

SCHEMBL778573

CC(C)OS(=O)(=O)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA9 Q16790 2/20 0.33
CA7 P43166 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CXCR2 P25025 2/20 0.32
CXCR1 P25024 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL5644122 0.87 ALDH1A1 (0.36) ALDH1A1
SCHEMBL575704 0.83 CA1 (0.33) ALDH1A1CA1CA2CA9CA7
SCHEMBL14779233 0.83 CA1 (0.43) ALDH1A1CA1CA2CA9CA7
SCHEMBL778307 0.81 CA1 (0.32) ALDH1A1CA1CA2CA9CA7
SCHEMBL1759309 0.81 CA1 (0.32) ALDH1A1CA1CA2CA9CA7
SCHEMBL28926829 0.80
SCHEMBL28896513 0.80 ALDH1A1 (0.33) ALDH1A1
SCHEMBL15282823 0.79 CA1 (0.36) ALDH1A1CA1CA2CA9CA7
SCHEMBL21801671 0.79 ALDH1A1 (0.36) ALDH1A1CA1CA2CA9CXCR2
SCHEMBL21801399 0.79 ALDH1A1 (0.36) ALDH1A1CA1CA2CA9CXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025099634-A1 PROCESS FOR PREPARING THE POLYMORPHIC FORM III OF TAPINAROF PROCOS S.P.A. (IT) 2025-05-15 WO claimed
CN-119372649-A Compatible display panel aluminum etching solution, and preparation method and application thereof 浙江奥首材料科技有限公司 2025-01-28 CN claimed
CN-117039163-A Lithium ion battery electrolyte and lithium ion battery 中国科学技术大学 2023-11-10 CN claimed
CN-116003429-A Preparation method of 9, 9-bis (trifluoromethyl) -2,3,6, 7-xanthene tetracarboxylic dianhydride 陕西泰合利华工业有限公司 2023-04-25 CN claimed
CN-105085264-A Asymmetric synthesis method for tanshinol ester derivative UNIV SHANGHAI JIAOTONG 2015-11-25 CN claimed
EP-1077926-B1 PROPYLISOPROPYL ACETAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM YISSUM RES DEV CO (IL) 2005-02-23 EP claimed
US-20030212131-A1 Propylisopropyl acetic acid and propylisopropyl acetamide stereoisomers, a method for their synthesis and pharmaceutical compositions containing them BIALER MEIR (IL) 2003-11-13 US claimed
US-6630602-B1 Racemic propylisopropyl acetic acid and propylisopropyl acetamide and their isomers in their racemic and stereospecific forms, for use in treatment of neurological and psychotic disorders, and affective disorders and to treat YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2003-10-07 US claimed
EP-1077926-A1 PROPYLISOPROPYL ACETIC ACID AND PROPYLISOPROPYL ACETAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2001-02-28 EP claimed
WO-1999054282-A1 PROPYLISOPROPYL ACETIC ACID AND PROPYLISOPROPYL ACETAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY (IL) 1999-10-28 WO claimed
US-12612391-B2 Cromolyn derivatives and uses thereof THE GENERAL HOSPITAL CORPORATION (US) 2026-04-28 US disclosed
US-12605471-B2 Cromolyn derivatives and related methods of imaging and treatment THE GENERAL HOSPITAL CORPORATION (US) 2026-04-21 US disclosed
US-12383528-B2 Cromolyn esters and uses thereof THE GENERAL HOSPITAL CORPORATION (US) 2025-08-12 US disclosed
EP-4577524-A1 METHODS OF MANUFACTURING KINASE INHIBITORS Insilico Medicine IP Limited (HK) 2025-07-02 EP disclosed
WO-2025099634-A1 PROCESS FOR PREPARING THE POLYMORPHIC FORM III OF TAPINAROF PROCOS S.P.A. (IT) 2025-05-15 WO disclosed
EP-0569046-A1 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension Pharmacia AB (SE) 1993-11-10 EP disclosed
US-5153180-A Used for treating aids BURROUGHS WELLCOME CO. 1992-10-06 US disclosed
EP-0364417-A1 Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension Pharmacia AB (SE) 1990-04-18 EP disclosed
WO-1990002553-A1 PROSTAGLANDIN DERIVATIVES FOR THE TREATMENT OF GLAUCOMA OR OCULAR HYPERTENSION PHARMACIA AB (SE) 1990-03-22 WO disclosed
US-4165332-A Preparation of aliphatic perchlorates and of trifluoromethane sulfonates THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1979-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605471-B2 Cromolyn derivatives and related methods of imaging and treatment PSEN1, APP, PSEN2 ALDH1A1 3176/4885CA1 49/4885CA2 245/4885
US-12612391-B2 Cromolyn derivatives and uses thereof HTT, PRNP, PSEN1 ALDH1A1 3162/4885CA1 826/4885CA2 355/4885
US-20030212131-A1 Propylisopropyl acetic acid and propylisopropyl acetamide stereoisomers, a method for their synthesis and pharmaceutical compositions containing them ADCYAP1R1, GRIN2A, PTGER1 ALDH1A1 171/4885CA1 1049/4885CA2 1385/4885
US-12383528-B2 Cromolyn esters and uses thereof PRNP, HTT, PSEN1 ALDH1A1 1915/4885CA1 873/4885CA2 4251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.