SCHEMBL14780546

SCHEMBL14780546

CN/C=N/S(=O)(=O)c1c(Cl)nc2ccc(C3CC3)nn12

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR139 Q6DWJ6 1/20 0.31
FYN P06241 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14374086 0.85 FYN (0.32) FYN
SCHEMBL14374054 0.80
SCHEMBL13106656 0.79 GPR139 (0.32) GPR139
SCHEMBL3165281 0.79 GPR139 (0.32) GPR139
SCHEMBL2067058 0.78 FYN (0.36) GPR139FYNKDM4EALDH1A1GAA
SCHEMBL2067424 0.76 TNF (0.35) GPR139FYNKDM4EALDH1A1GAA
SCHEMBL2065980 0.69 FYN (0.35) FYN
SCHEMBL14374055 0.68 TNF (0.40) KDM4EALDH1A1
SCHEMBL2067049 0.68 FYN (0.34) GPR139FYN
SCHEMBL14347094 0.68 LMNA (0.38) KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399381-B2 Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-03-19 US disclosed